The use of genomic sequencing panels to personalise cancer treatment is beneficial in only 5% of the patients in whom they are currently used

by CNIO - Centro Nacional de Investigaciones Oncológicas

The study shows that when clinical recommendations are followed, genomic sequencing panels increase the efficacy of treatments and patient survival

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Diferencias genómicas entre tumores primarios y metastásicos

by Revista Genética Médica

Un equipo de investigadores del Centro Médico Universitario de Utrecht, el Instituto de Oncología Vall d’Hebron y la Fundación Médica Hartwig ha analizado el genoma completo de los 23 tipos de c...

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A programme that looks for the most effective drugs for each patient’s cancer helps to personalise cancer treatments

by CNIO - Centro Nacional de Investigaciones Oncológicas

Developed by CNIO and the University of Vigo, the PanDrugs2 programme analyses alterations in tumour genes, relates them to existing available drugs, and reports on the most suitable ones

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Novel AKT inhibitor combined with standard hormone therapy shows promise for patients with pre-treated metastatic HR+/ HER2- breast cancer

by VHIO

The phase III randomized multi-center CAPItello-291 assessed the efficacy and safety of novel AKT inhibitor capivasertib plus fulvestrant in patients with advanced HR+/ HER2- breast cancer who had pro...

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Researchers from CIC bioGUNE reveal structural insights into the immune modulator Siglec-15 and its interaction with T cells

by CIC bioGUNE

The study, published in the journal Nature Communications, opens the door to the development of effective drug candidates that fully harness the therapeutic potential of Siglec-15. This knowledge will...

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La UCLM codirige un estudio que demuestra cómo un gen es clave para la radio resistencia en células tumorales

by Universidad de Castilla-La Mancha

Han demostrado en un estudio como el gen MAPK11 es clave para entender los fenómenos de radio resistencia en las células tumorales al controlar el proceso de senescencia, una de las respuestas clave...

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Nuage Therapeutics raises €12M in Seed Financing led by Sofinnova Partners and Asabys

by Asabys Partners

Nuage Therapeutics (“Nuage”) announces today the successful closing of a €12 million Seed financing to support the development of its lead program and validate its pioneering drug discovery plat...

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Tagworks Pharmaceuticals Announces $65 Million in Series A Financing led by Ysios Capital and Gilde Healthcare, to Advance Click-to-Release Therapeutics

by Ysios Capital

Tagworks Pharmaceuticals BV (“Tagworks”), the pioneer of Click-to-Release chemistry designed to deliver more effective and safer systemic therapies, today announced a $65 million Series A financin...

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OneChain Immunotherapeutics secures €6.7M in pre-series A funding round led by Invivo Capital

by OneChain Immunotherapeutics

OneChain Immunotherapeutics (OCI), a clinical stage biotech company focused on the development of CAR-T candidates for the treatment of oncological diseases, today announced the closing of a €6.7 mi...

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Demonstration of the usefulness of a biomarker in the prognosis and possible treatment of glioma

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

It has been determined that a specific type of protein, IκBα, is a prognostic marker in one of the types of cancer with the highest mortality, diffuse glioma. Specifically, in the case of patients w...

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New EIC project to improve CAR T therapies in solid tumors

by Centro Singular de Investigación en Química Biológica y Materiales Moleculares

CiQUS researchers will participate in CAR T-REX, a new project funded with €2.7M by the European Innovation Council (EIC) to develop novel, scalable CAR T cell therapies with increased efficacy for ...

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Una nueva combinación de inmunoterapia mejora la eficacia en modelos animales de cáncer de hígado

by CIMA - Centro de Investigación Médica Aplicada

El estudio experimental ha demostrado que las inmunoterapias que se aplican actualmente en los pacientes tienen un efecto parcial en este nuevo modelo animal. Sin embargo, su eficacia aumenta con comb...

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