A new method expands the potential of a family of compounds in medicine and materials science

by Universitat de Barcelona

Teams from the University of Barcelona and the University of Girona, in collaboration with Nanjing University (China), have developed an innovative method for selectively modifying these boron-rich mo...

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A multi-omic study rules out the role of immature cells in resistance to cancer treatment

by Cima Universidad de Navarra

The results of this study by Cima Universidad de Navarra help improve the accuracy of diagnosis and monitoring for patients with multiple myeloma and primary systemic amyloidosis

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Targeted therapies improve efficacy in early-phase clinical trials driven by molecular patient selection

by VHIO

Researchers at VHIO have published an article in the journal European Journal of Cancer on the evolution of targeted therapies in early-phase clinical trials. The study shows a progressive improvement...

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KRAS degradation induces rapid lung cancer regression in preclinical mouse models

by IRB Barcelona - Instituto de Investigación Biomédica

It has been demonstrated that eliminating mutated KRAS protein using PROTACs induces rapid tumour regression in mouse models of lung adenocarcinoma

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Promising results for a novel bispecific antibody

by VHIO

The HERIZON-GEA-01 open-label, phase 3 clinical trial was designed to compare first-line treatment with the bispecific antibody zanidatamab plus chemotherapy with or without PD‐1 monoclonal antibody...

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Fat molecule inside cell nucleus shifts with cell division

by Centre for Genomic Regulation

invResearchers have shown that a type of fat molecule, long associated with signalling at the cell's outer membrane, also operates inside the nucleus on a schedule that matches the rhythm of cell divi...

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Un estudio liderado por el Hospital público 12 de Octubre asocia el uso de antibióticos de amplio espectro con peores resultados clínicos en pacientes con mieloma múltiple

by Hospital Universitario 12 de Octubre

Han demostrado por primera vez que la administración de antibióticos de amplio espectro, antes de iniciar un tratamiento con anticuerpos biespecíficos —una forma avanzada de inmunoterapia—, se ...

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Chronic smokers are not prepared to quit smoking

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

Three out of four people selected to participate in a lung cancer screening programme because they were at high risk of developing the disease want to quit smoking, but almost 80% rule out quitting if...

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Researchers develop a blood test that can detect pancreatic cancer within minutes

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

This is the first trial of a diagnostic test that identifies, in blood plasma, a protein (AXL) that acts as a biomarker for pancreatic ductal adenocarcinoma, the most common and deadliest form of panc...

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ORYZON initiates patient enrollment in IDEAL Phase II trial of iadademstat in essential thrombocythemia

by Oryzon Genomics

Oryzon Genomics a clinical-stage biopharmaceutical company and a global leader in epigenetics, today announced that the first patient has been enrolled in IDEAL, its Phase II study evaluating iadadems...

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Immunity against measles: a tool against cancer

by Universitat Politècnica de València

A team led by the UPV proposes harnessing the immunological memory generated by vaccination to help the body recognise and eliminate tumour cells

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