El Instituto Catalán de Oncología trata al primer paciente en Cataluña de mieloma múltiple con células CAR-T fuera de un ensayo clínico

by ICO - Institut Català d'Oncologia

Hasta ahora estos tratamientos sólo se podían realizar en ensayos clínicos que probaban su efectividad. Por último, y después de los buenos resultados, la Agencia Española del Medicamento y Prod...

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Dr Ana Caballero from the Haematology Service Presents Data on the Efficacy of the Academic CAR T-cell Therapy HSP-CAR30 at the ASH Congress

by Hospital de la Santa Creu i Sant Pau

It has been presented the phase I/II clinical trial of the HSP-CAR30 treatment for patients with refractory or relapsed Hodgkin lymphoma and CD30+ T-cell lymphoma. This innovative cellular therapy, a ...

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A new dual CAR-T therapy is developed against non-Hodgkin lymphoma

by Fundació Clínic per a la Recerca Biomèdica

Researchers at IDIBAPS- Hospital Clínic have developed and validated a new CAR-T therapy called ARI0003 at a preclinical level. The new therapy combines two therapeutic targets to boost effectiveness...

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Vaccines, gene-editing-based therapies, and immunotherapies will transform the current landscape of cancer treatment

by Asebio

Biotechnology has radically changed the treatment of many types of tumors, evolving from highly aggressive and non-specific treatments to those tailored to the unique characteristics of each patient. ...

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CNIO researchers seek more effective immunotherapies for children with cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

CAR-T therapies have been effective in 60% of the pediatric patients who have received them; “we study why they have not worked in the rest,” explain CNIO researchers Cristina Aguirre and Andrés ...

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Una paciente con neuroblastoma lleva 18 años en remisión tras una terapia con CAR-T

by Agencia Sinc

Este tumor pediátrico poco frecuente tiene una alta tasa de recaída con los tratamientos convencionales. Según los autores del estudio publicado en Nature Medicine, se trata de la remisión más p...

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Integra Therapeutics, first company to move into Advanced Therapies Platform at SJD Barcelona Children's Hospital

by Integra Therapeutics

Integra Therapeutics has developed the FiCAT gene-writing platform to develop cell therapies for autoimmune and oncology diseases and gene therapies for rare diseases. The company recently announced a...

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Neurona Unveils Phase 3 EPIC Study for NRTX-1001 Cell Therapy in Epilepsy

by Ysios Capital

Based on alignment gained with FDA under the Regenerative Medicine Advanced Therapy (RMAT) designation, Neurona plans to conduct the Phase 3 EPIC (EPIlepsy Cell therapy) trial as the primary basis for...

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Thermo Fisher Scientific Launches CorEvitas Clinical Registry and Biorepository in Systemic Lupus Erythematosus

by Thermo Fisher Scientific

Thermo Fisher Scientific Inc, today announced the launch of the CorEvitas Systemic Lupus Erythematosus (SLE) Registry. The multi-center, prospective registry leverages the CorEvitas rheumatology physi...

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La Arrixaca y el IMIB en la élite de la fabricación de fármacos CAR-T contra el cáncer

by Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca

Ahora se da un paso más y a la administración de los fármacos se unirá también la producción de los mismos, convirtiéndose en breve la Arrixaca y la Sala Blanca IMIB-Pascual Parrilla en uno de ...

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A new CAR-T-cell therapy tricks cancer cells with a decoy to increase treatment efficiency in B-cell Acute Lymphoblastic Leukaemia

by CNIO - Centro Nacional de Investigaciones Oncológicas

Treatment of B-cell Acute Lymphoblastic Leukaemia has improved thanks to CAR-T therapies, but relapse is still very common. An international team has now test in animal models a new "promising therape...

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Vall d’Hebron shows long-term safety of CAR-T therapy in aggressive lymphoma patients

by VHIO

The results show the need for continuous monitoring of patients to detect and manage possible adverse effects occurring months and years after treatment.

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