Abundant ‘secret doors’ on human proteins could reshape drug discovery

by Centre for Genomic Regulation

A ground-breaking new technique developed by researchers at the Centre for Genomic Regulation (CRG) in Barcelona has revealed the existence of a multitude of previously secret doors that control prote...

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New non-hormonal contraceptive pill for men?

by Fundació Clínic per a la Recerca Biomèdica

Recently, a male contraceptive pill was tested on mice that is nearly 100% effective and which allows fertility to be restored approximately one month after stopping administration. The study was perf...

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CNIO researchers find a way to increase effectiveness of radiotherapy for brain metastasis

by CNIO - Centro Nacional de Investigaciones Oncológicas

They found that a simple blood test can help detect patients with resistance to brain radiotherapy and identified a drug that might reverse it. A multi-centre clinical study is now under way to valida...

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Triple therapy shows major benefits in the treatment of metastatic prostate cancer

by VHIO

A study performed by the European PEACE consortium, in which the Vall d’Hebron Institute of Oncology (VHIO), part of the Vall d’Hebron Campus, participated, has shown how adding abiraterone to and...

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The coming revolution: synthetic DNA and RNA for therapeutic and diagnostic applications

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

The discovery of the mRNA vaccines for the treatment of coronavirus, as well as new medicines for the treatment of genetic diseases, has been important in the quest of solutions for undrugable disease...

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Un equipo del CSIC produce anticuerpos neutralizantes eficaces contra la covid-19

by CSIC - Centro Superior de Investigaciones Científicas

Investigadores del CSIC han obtenido anticuerpos neutralizantes eficaces frente a las variantes más virulentas del SARS-CoV-2 y que pueden utilizarse como terapia en pacientes de covid-19. Los invest...

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MCLA-158, the first clinical candidate screened in organoids targeting cancer stem cells of solid tumors

by IRB Barcelona - Instituto de Investigación Biomédica

An international consortium, led by IRB Barcelona and the biotechnology company Merus, reveals the preclinical data that has led to the discovery of MCLA-158 and its mechanism of action.

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Promising drug against childhood osteosarcoma, a type of bone cancer with a poor prognosis

by Fundació Bosch i Gimpera

The UB team has synthesized a new compound that has shown excellent results in in vitro trials with cancer cell samples, as it has managed to inhibit the activity of human cells connected to osteosarc...

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Se inicia el ensayo clínico para el primer tratamiento del síndrome del ovario poliquístico

by Fundació Sant Joan de Déu

La Dra. Lourdes Ibáñez, investigadora del IRSJD y endocrinóloga en el Hospital Sant Joan de Déu Barcelona, lidera un ensayo clínico internacional que evaluará un tratamiento pionero a nivel mund...

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A study participated by Vall Hebron made possible the approbation of a new treatment for severe pediatric asthma

by Vall d’Hebron

An international clinical trial has demonstrated the effectiveness of dupilumab in reducing patients’ asthmatic exacerbations, improving their and their relatives quality of life

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La Fundación Jiménez Díaz activa el estudio INBRX-109, un innovador ensayo clínico para el tratamiento del condrosarcoma convencional avanzado

by Fundación Jiménez Díaz

La Fundación Jiménez Díaz ha puesto en marcha recientemente el estudio INBRX-109, dirigido a demostrar el beneficio de este fármaco en condrosarcoma convencional avanzado, convirtiéndose en el pr...

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In vitro and in vivo assays identifies a combination of two drugs that have the potential to improve the treatment of MPNST

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

The screening of a drug library against peripheral nerve sheath tumors identifies the combination of two compounds that reduce tumor growth in two mouse models.

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