Latest Drug discovery biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

A drug that lowers blood lipids could help treat the world’s most common liver disease

by Universitat de Barcelona

According to the new paper, pemafibrate it could also open a new therapeutic avenue to address MASLD in the context of drug repositioning, i.e. the use of known and approved drugs in clinical practice...

OXOART2, clinical study of Oxolife, selected as one of the most outstanding presented at the 40th annual meeting of ESHRE

by CATALONIA.HEALTH

2 years ago
OXO-001, Oxolife, OXOART2

Oxolife shows the efficacy of a non-hormonal oral drug that increases the rate of embryo implantation, pregnancy and live birth rates among infertile women who are undergoing in vitro fertilization (I...

Identifican nuevos marcadores para el diagnóstico precoz de patologías hepáticas graves tras la curación de la hepatitis C

by CSIC - Centro Superior de Investigaciones Científicas

2 years ago
hepatitis C (VHC), carcinoma hepatocelular

Un estudio del CSIC describe genes como marcadores del estado del hígado tras la eliminación del virus de la hepatitis C crónica, que puede dar lugar a enfermedades hepáticas graves como la cirros...

The immunopathology unit of IDIVAL delves into the effectiveness of certain treatments for patients with giant cell arteritis

by Instituto de Investigación Marqués de Valdecilla

2 years ago
giant cell arteritis (GCA), inhibitors of janus kinases (iJAK), tocilizumab, aortitis

Two new publications show results on the effectiveness of inhibitors of janus kinases (iJAK) in giant cell arteritis (GCA) and on the effectiveness of the antibody tocilizumab for aortitis in GCA.

New discovery for treating Acetaminophen-induced liver damage from overdose

by CIC bioGUNE

2 years ago
Acetaminophen, liver damage, neddylation, MLN4924, cardiolipin

The study, recently published in Cell Reports Medicine, has uncovered a new treatment for liver damage caused by acetaminophen (APAP) overdose, potentially eliminating the need for liver transplants i...

Down syndrome linked to changes in mobile DNA fragments

by Centre for Genomic Regulation

2 years ago
Down syndrome, retrotransposons, lamivudina

A study conducted by IrsiCaixa —a centre jointly supported by the "la Caixa" Foundation and the Department of Health of the Generalitat de Catalunya— and the Centre for Genomic Regulation (CRG) de...

HIF-2α inhibitor improves outcomes in patients with previously treated advanced clear cell renal carcinoma

by VHIO

2 years ago
hypoxia-inducible factor 2α (HIF-2α), belzutifan, everolimus

Results of the phase III LITESPARK-005 clinical trial show that treatment with belzutifan versus everolimus significantly improves progression-free survival in patients with advanced clear cell renal ...

Validation of the efficacy of a treatment for migraine in real clinical practice

by Fundació Clínic per a la Recerca Biomèdica

2 years ago
migraine, galcanezumab, calcitonin gene-related peptide (CGRP)

Researchers at the Clínic-IDIBAPS coordinated a study that highlights the efficacy of migraine treatment with a monoclonal antibody, galcanezumab, in routine clinical practice.

Un fármaco para la esclerosis restaura el daño cardíaco en ratones tras un infarto

by Agencia Sinc

2 years ago
acetato de glatiramero, insuficiencia cardíaca

Muestran cómo la reutilización de un medicamento para esta enfermedad del sistema nervioso protege a las células musculares cardíacas de la muerte celular inducida por la restricción de sangre, r...

Different hierarchical reconfigurations in the brain by psilocybin and escitalopram for depression

by UPF - Universitat Pompeu Fabra

2 years ago
depression, psilocybin and escitalopram

Two pharmacological treatments used for depression affect the brain in completely different ways, shedding light on how the depressed brain gets rebalanced, according to a paper published in the journ...

Bellvitge colidera un ensayo internacional que puede cambiar el tratamiento de la insuficiencia cardíaca

by Hospital Universitari de Bellvitge

2 years ago
finerenona, insuficiencia cardíaca.

El ensayo ha confirmado los beneficios de un fármaco, la finerenona, en un importante segmento de los casos de insuficiencia cardíaca.

Un inhibidor selectivo de PARP1 muestra una potente y duradera actividad antitumoral en modelos preclínicos derivados de pacientes

by VHIO

2 years ago
inhibidor selectivo de PARP1 saruparib (AZD5305), olaparib, BRCA1/2

Demuestran que el inhibidor selectivo de PARP1 saruparib (AZD5305) produce una respuesta antitumoral más potente y duradera que olaparib, un inhibidor de primera generación actualmente aprobado para...