New tool to boost cancer immunotherapy effects

by UPF - Universitat Pompeu Fabra

A team of researchers from the Hospital del Mar Research Institute, the Universitat Autònoma de Barcelona and the Pompeu Fabra University has developed a new tool that allows modifying these NK cells...

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A new CAR-T-cell therapy tricks cancer cells with a decoy to increase treatment efficiency in B-cell Acute Lymphoblastic Leukaemia

by CNIO - Centro Nacional de Investigaciones Oncológicas

Treatment of B-cell Acute Lymphoblastic Leukaemia has improved thanks to CAR-T therapies, but relapse is still very common. An international team has now test in animal models a new "promising therape...

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Positive Data from Phase 1 Trial of Bel-sar in Patients with Non-Muscle-Invasive Bladder Cancer (NMIBC) Presented at the 40th Annual European Association of Urology Congress

by Ysios Capital

Aura Biosciences today announced positive data from a completed Phase 1 window of opportunity trial of bel-sar (AU-011) in patients with NMIBC. These data were presented by Dr. Seth Lerner as a late b...

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Vall d’Hebron shows long-term safety of CAR-T therapy in aggressive lymphoma patients

by VHIO

The results show the need for continuous monitoring of patients to detect and manage possible adverse effects occurring months and years after treatment.

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IDIBAPS launches an AECC-funded excellence programme to improve the response to immunotherapy in cancer

by Fundació Clínic per a la Recerca Biomèdica

On Thursday 13 March 2025, IDIBAPS held the first meeting of the new research project ‘AECC-IDIBAPS Excellence Programme: Immunotherapy Against Cancer’. Funded by the Spanish Association Against C...

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Una investigación del CNIO descubre cómo el melanoma y otros tumores logran ocultarse y resistir a la inmunoterapia

by CNIO - Centro Nacional de Investigaciones Oncológicas

Las células de melanoma, el cáncer de piel más agresivo, producen una proteína que bloquea el reconocimiento y eliminación del tumor por parte del sistema inmunitario, las defensas naturales del ...

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Extracellular vesicles, key in maternal-embryonic communication, open new possibilities for improving assisted reproduction

by CIC bioGUNE

The research identified differences in the proteins of EVs from oviductal fluid, crucial for embryonic development and maternal-embryo interaction.

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The potential of exosomes in regenerative medicine

by Sermes CRO

Regenerative medicine has advanced significantly in recent decades, and one of the most promising discoveries in this field is exosomes. These tiny extracellular vesicles are revolutionizing how we un...

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A Targeted Nanotoxin Activates the Immune Response and Slows Colorectal Cancer Growth in Preclinical Models

by Hospital de la Santa Creu i Sant Pau

Researchers from the Sant Pau Research Institute (IR Sant Pau) have demonstrated, in a preclinical study, the effectiveness of a targeted nanotoxin in inhibiting colorectal cancer growth. The study, p...

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Investigadores del IMIBIC identifican características moleculares clave del cáncer de mama asociado al embarazo que podrían mejorar su abordaje terapéutico

by Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)

Identifican características clínicas y moleculares específicas del cáncer de mama asociado al embarazo (PABC) que abren la posibilidad de orientar futuras estrategias terapéuticas personalizadas ...

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Ensayo pionero para tratar con un nuevo CAR-T académico a pacientes con mieloma múltiple en recaída

by Instituto de Investigación Biomédica de Salamanca - IBSAL

La colaboración del Complejo Asistencial Universitario de Salamanca a través del IBSAL y del Hospital Virgen de Rocío, mediante el Instituto de Biomedicina de Sevilla, ha logrado la financiación d...

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Hospital Clínic-IDIBAPS, pioneer in CAR T-cell therapies for cancer with over 500 patients treated

by Fundació Clínic per a la Recerca Biomèdica

Hospital Clínic-IDIBAPS is the only hospital in Europe to have fully developed two academic CAR T-cell therapies that have been approved by a regulatory authority (AEMPS).

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