ASH 2025: safety and efficacy data from a phase 1 study show promise of next-generation CAR-T cell therapy in patients with refractory B-cell acute lymphoblastic leukemia

by VHIO

Safety and efficacy data from a phase 1 multicenter study evaluating rapcabtagene autoleucel, an investigational next-generation CD19-directed CAR-T cell therapy that is manufactured in 48 hours using...

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La Comunidad de Madrid detecta las causas que explican la persistencia de síntomas en celiacos que siguen una dieta sin gluten

by Hospital Universitario La Paz - Carlos III

La Comunidad de Madrid ha detectado las causas que explican la persistencia de síntomas en celiacos pese a que sigan una dieta sin gluten. Un equipo de investigadores liderados por el Instituto Madri...

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A new study reveals that prostate cancer alters the function of the cells that support blood vessels

by CIC bioGUNE

The new study shows that pericytes do not disappear, instead, they are reprogrammed. This dysfunction is regulated by a cytokine (a secreted protein) called TGF-β, which acts as a messenger between t...

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Four innovative Clínic-IDIBAPS projects funded by the Department of Health to advance medical technology and cell therapies

by Fundació Clínic per a la Recerca Biomèdica

Professionals from Hospital Clínic-IDIBAPS are leading two projects in medical technology innovation and two in advanced drug and therapy development, which have received funding through the Strategi...

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Investigadores españoles publican dos avances clave que mejoran la eficiencia de las terapias de edición génica en enfermedades de la sangre

by Fundación Jiménez Díaz

Un nuevo protocolo sin quimioterapia logra injertos más seguros y eficaces en modelos de inmunodeficiencia y anemia por deficiencia de piruvato quinasa

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Desarrollados nuevos modelos experimentales para avanzar en el tratamiento del cáncer de hígado

by Professional Newco

El TGF-beta juega un papel fundamental en el inicio y progresión del hepatocarcinoma, y la inhibición de su acción podría presentar un interés terapéutico. Sin embargo, su actividad es compleja ...

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The Clínic carries out a new pioneering therapy to reduce the risk of rejection in kidney transplants

by Fundació Clínic per a la Recerca Biomèdica

The aim of the study is to identify 30 highly sensitized patients, who will undergo a leukapheresis, a process that allows white blood cells to be separated and extracted from a patient's blood. From ...

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An international study shows that combining immunotherapy with chemotherapy improves survival in stomach cancer

by Instituto de Investigación Marqués de Valdecilla

The results confirm that combining durvalumab with FLOT (fluorouracilo, leucovorina, oxaliplatina y docetaxel) is not only effective but also safe for patients.

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Un estudio identifica el papel clave del colesterol en la migración de las células del sistema inmunológico

by Centro Nacional de Biotecnología (CNB)

Investigadores del CNB-CSIC han descubierto que los niveles de colesterol en la membrana celular afectan a la capacidad de las células inmunitarias para migrar a los tejidos donde son necesarias

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Neutrophils are less aggressive at night, explaining why nighttime heart attacks cause less damage than daytime events

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

A CNIC study reveals that neutrophils—a type of immune cell—are less aggressive at night, explaining why nighttime heart attacks are less severe than those occurring during the day

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