They identify a new oncogenic and treatable fusion in aggressive hematological tumors

by Universidad Autónoma de Madrid

The researchers demonstrate that the SEPTIN6::ABL2 fusion gene induces both the proliferation and survival of different hematopoietic cell models, behaving as an oncogenic fusion gene and contributing...

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IDP Pharma starts clinical trials of its first-in-class IDP-121 drug in hematological cancers and opens a financing round of €1M for the first phase of the study

by Parc Científic de Barcelona

The Spanish Agency of Medicines and Medical Devices has authorised the clinical trial of IDP-121, the first drug blocking and degrading a key oncoprotein in several hematological tumors, including mul...

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A plant protein is capable of dissolving protein aggregates related to various human pathologies

by CRAG

CRAG researchers discover that the plant protein MC1 is able to dissolve insoluble clusters of proteins involved in different diseases.

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A carbohydrate sequence capable of folding into a stable secondary structure

by CIC bioGUNE

This work opens the door to endow glycans with new properties that could step up completely new perspectives in biomedicine and materials science.

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Maternal Health Experts Warn of an Overlooked Global Health Emergency: The Alarming Lack of Progress in Reducing Maternal Deaths

by ISGlobal - Instituto de Salud Global de Barcelona

It has published an opinion piece in the British Medical Journal (BMJ) warning of the worrying lack of progress in reducing preventable maternal deaths worldwide. This situation, they say, has been ex...

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Un ensayo clínico muestra la seguridad y eficacia del dispositivo de diálisis hepática DIALIVE en pacientes con insuficiencia hepática aguda sobre crónica, para quienes la única opción actual es el trasplante de hígado

by INCLIVA

Un ensayo clínico internacional controlado aleatorizado de Fase I, en humanos, utilizando DIALIVE -un novedoso dispositivo de diálisis hepática-, demostró su potencial como terapia modificadora de...

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El consumo frecuente de frutos secos protege contra el deterioro cognitivo 

by Universitat Rovira i Virgili

Los resultados de este nuevo estudio respaldan investigaciones anteriores que sugieren que los frutos secos pueden tener un efecto beneficioso sobre la cognición y la prevención del deterioro cognit...

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New generation of antibacterial materials for medical implants developed

by Universitat Politècnica de Catalunya

The UPC’s Biomaterials, Biomechanics and Tissue Engineering Group (BBT) leads the international project Bio-TUNE, which aims to develop multifunctional materials with high antibacterial potential an...

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Novel platform shows preclinical and early clinical promise in accelerating the production of more effective CAR-T cell therapy

by VHIO

Researchers from VHIO's Experimental Hematology Group have participated in the development of a new technology to manufacture CAR-T cells or genetically modified lymphocytes to attack tumor cells, whi...

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The CAR T-cell therapy from the Hospital Clínic-IDIBAPS for multiple myeloma is effective in patients with refractory disease

by Fundació Clínic per a la Recerca Biomèdica

A multicentre study led by the Hospital Clínic Barcelona-IDIBAPS demonstrates the efficacy of the CAR T-cell therapy ARI0002h in treating patients with multiple myeloma resistant to standard treatmen...

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An international team identifies the mutations that cause the most frequent congenital heart defects

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

The researchers conclude that the identified association between MIB1 and bicuspid aortic valve highlights the important role of the NOTCH signaling pathway in this congenital defect and the potential...

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Una nueva técnica permite hallar por primera vez bacterias con interés farmacéutico en babosas marinas

by CSIC - Centro Superior de Investigaciones Científicas

El Instituto de Biología Integrativa de Sistemas (I2SysBio, CSIC-UV) detecta en nudibranquios una bacteria simbiótica con genes para producir moléculas con aplicacionfarmacológicas

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