Latest Central Nervous System biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

Proteínas anómalas en el líquido cefalorraquídeo de personas con ELA y demencia frontotemporal

by Revista Genética Médica

3 months ago
proteína TDP-43, esclerosis lateral amiotrófica (ELA), demencia frontotemporal (DFT), exones crípticos

Las proteínas en cuestión se construyen a partir de exones “crípticos”, es decir, partes anormales del ARN, las instrucciones de la célula para construir proteínas. Los exones crípticos apar...

A study finds a molecular mechanism related to neuronal death

by Universitat de Barcelona

3 months ago
Alex3/Gαq, Gq protein with the Alex3 mitochondrial protein, G protein-coupled receptors (GPCR), Alex3 gene

It has been identified, for the first time, a molecular complex that regulates the transport of mitochondria within neurons and neuronal death. The discovery of the complex, exclusively present in the...

Cirugía pionera para tratar la apnea del sueño

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

3 months ago
CPAP (presión positiva continua en las vías respiratorias), apnea del sueño, Nyxoah-Genio

Se trata de implantar un neuroestimulador para poder actuar sobre el nervio que controla el movimiento de la lengua. De esta manera, se puede evitar que bloquee el paso del aire durante el sueño.

Neurona Therapeutics Raises $120M to Advance Groundbreaking Pipeline of Regenerative Cell Therapy Candidates for Chronic Neurological Disorders

by Ysios Capital

3 months ago
NRTX-1001, Neurona Therapeutics, mesial temporal lobe epilepsy (MTLE)

Proceeds from the financing will be used to advance the company’s pipeline of wholly-owned, off-the-shelf cell therapies for multiple indications, including its lead investigational candidate, NRTX-...

The analysis of biological networks allows understanding the complexity of multiple sclerosis

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

3 months ago
MK03, multiple sclerosis

An international study has used a computational biology tool that, by analysing a multitude of biological data from multiple sclerosis patients ranging from genetic information to the whole organism, ...

An anticancer drug opens a new path for the treatment of Parkinson’s

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

3 months ago
metabolite M324, Rucaparib, protein α-synuclein, Parkinson

The fact that M324 is capable of reducing the abnormal accumulation of α-synuclein in neurons derived from stem cells of a Parkinson’s patient, highlights the therapeutic potential of this metaboli...

An ultrasound scan at the end of pregnancy allows serious neonatal complications to be avoided in babies at risk

by Hospital Sant Joan de Déu

2 months ago
RATIO37, cerebroplacental ratio (CPR), Doppler

A study conducted by SJD Barcelona Children's Hospital and Hospital Clínic de Barcelona has demonstrated that inducing labour at term in such cases reduces these complications and ICU admissions of t...

El impulso de pruebas genéticas mejora el diagnóstico de las causas de la epilepsia

by Hospital Universitari de Bellvitge

2 months ago
epilepsia, Hospital Universitario de Bellvitge (HUB)

Las Unidades de Epilepsia y de Genética Clínica del Hospital Universitario de Bellvitge han puesto en marcha estudios genéticos multidisciplinarios para identificar la causa de la epilepsia, un tra...

Científicos de alto nivel aúnan esfuerzos para estudiar los aspectos más desconocidos del cerebro humano en un consorcio con la participación del CBC de la UPF

by UPF - Universitat Pompeu Fabra

2 months ago
consorcio BRADY

Con esta finalidad, se ha constituido el consorcio de investigadores de alto nivel BRADY (Brain Dynamics), en el que participa el Centre for Brain and Cognition (CBC) de la UPF. Este consorcio coordi...

Tumor-on-chip technology validated to test the effect of a drug against glioblastoma

by IRB Lleida. Institut de Recerca Biomèdica

2 months ago
NNC-55-0396, glioblastoma, Tumor-on-chip

This technology makes it possible to evaluate the efficacy of drugs in biological models that represent at the microscale the conditions under which a tumor develops in the human body.

Differences found in gut microbiota between men and women with ischemic stroke

by Hospital de la Santa Creu i Sant Pau

2 months ago
gut microbiota, ischemic stroke, Fusobacteriaceae

This study is the first to indicate that there are differences in gut microbiota between men and women who have suffered an ischemic stroke, identifying high levels of Fusobacteriaceae in women as a s...

Researchers identify a modulator drug of the immune system to be potentially useful to block Parkinson’s disease

by Universitat de Barcelona

2 months ago
astrocytes, dopamine, inflammatory cytokine IL-6, tocilizumab

A study on Parkinson’s published in the Journal of Clinical Investigation Insight reveals brain cells called astrocytes to be reactive, attacking and removing nervous cells that generate dopamine in...