Niveles elevados de colesterol intracelular promueven la acumulación de mitocondrias defectuosas que se observa en enfermedades como el Alzheimer

by Fundació Clínic per a la Recerca Biomèdica

Un estudio del IDIBAPS-IIBB-CSIC ha identificado un mecanismo que favorece la acumulación de mitocondrias defectuosas que se observa en enfermedades como el Alzheimer. Lo publica Molecular Neurodegen...

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Of 72 antivirals tested in the laboratory, plitidepsin proves to be the most effective in preventing SARS-CoV-2 replication

by IrsiCaixa

IrsiCaixa and CReSA, as part of the consortium formed by these two institutions, together with the BSC, have tested 72 antivirals with the aim of assessing their ability to prevent infection by SARS-C...

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A molecular classification predicts the prognosis and the benefit of a cell cycle inhibitor in metastatic breast cancer

by Fundació Clínic per a la Recerca Biomèdica

In a study published in the Journal of Clinical Oncology, researchers from the Hospital Clínic-IDIBAPS-UB and SOLTI showed the predictive capacity of the 4 molecular subtypes of breast cancer (Lumina...

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The EMBO Journal. A new mechanism that explains the toxicity of USP7 inhibitors, which are under development for the treatment of cancer, unveiled

by CNIO - Centro Nacional de Investigaciones Oncológicas

​The researchers have discovered that USP7 inhibitors -under development by several pharmaceutical companies for the treatment of cancer- trigger a premature activation of cell cycle proteins, leadi...

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Measuring RNA modifications opens new research avenues for cancer detection

by Centre for Genomic Regulation

​Researchers at the Centre for Genomic Regulation (CRG) have developed a new method to measure the abundance of RNA modifications in much finer detail than previously possible. The findings will adv...

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Fagocitosis y salud celular

by Labo'Life

​Ante una agresión a nuestro organismo, sea de naturaleza externa (ej. patógenos, tóxicos) o interna (ej. células procancerígenas), el sistema inmune nos defiende con una serie de procesos, com...

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Comparison between 2D and 3D Cultures

by CYTES BIOTECHNOLOGIES, SL.

Within the pharmaceutical industry, business firms and organizations need to test the toxicity of the drugs they create. The common method used is in vitro testing employing Primary Human Hepatocytes ...

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CSIC Scientists propose a new strategy to regulate the cells communication network

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

A study performed by researchers at the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) from the Spanish National Research Council (CSIC) in collaboration with Stony Brook University (USA) p...

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Investigadores del IIBB-CSIC-IDIBAPS lideran una revisión de consenso internacional sobre la hepatotoxicidad por medicamentos

by Fundació Clínic per a la Recerca Biomèdica

El equipo, liderado por José C. Fernandez-Checa, jefe del grupo Regulación mitocondrial de la muerte celular y la esteatohepatitis, ha realizado una revisión de consenso internacional sobre hepato...

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Sartorius acquires cell culture specialist Xell AG

by Sartorius Stedim Spain

Extension of the Sartorius cell culture media business with a focus on media for gene therapeutics and vaccines

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Centriole instability might contribute to some cases of microcephaly

by IRB Barcelona - Instituto de Investigación Biomédica

Researchers at IRB Barcelona identify the γ-tubulin ring complex (or γTuRC) as responsible for providing stability to centrioles. Published in Nature Communications, this study offers a new per

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