Latest Clinical trials biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

La fisioterapia especializada en conjunto con la terapia cognitivo-conductual mejora la calidad de vida de los pacientes con trastornos del movimiento funcional

by Instituto de Biomedicina de Sevilla - IBIS

2 years ago
terapia cognitivo-conductual

Se demuestra por primera vez en un ensayo clínico que un abordaje multidisciplinar que integre fisioterapia específica y terapia cognitivo-conductual es eficaz para mejorar los síntomas y aspectos ...

Palobiofarma is pleased to announce today positive top-line results in a Phase 2 trial of the novel oral drug PBF-680 in patients with moderate-to-severe COPD.

by Palobiofarma

2 years ago
PBF-680, COPD, blood eosinophil count (BEC), TNFalfa

Primary endpoint was achieved, with PBF-680 demonstrating a statistically significant reduction in blood eosinophil count over 4 weeks. Reduction in blood eosinophil count correlated with statisticall...

IBRILATAZAR (ABTL0812) from AbilityPharma increases chemotherapy effectiveness by 40% in patients with endometrial cancer

by AbilityPharma

2 years ago
ibrilatazar (ABTL0812), PI3K, endometrial cancer

The trial evaluated the safety and efficacy of ibrilatazar (ABTL0812) combined with paclitaxel/carboplatin in 51 patients with advanced or recurrent endometrial cancer, across 9 leading oncology hospi...

ORYZON announces first patient dosed in an Investigator-initiated Phase Ib study of iadademstat in first-line acute myeloid leukemia

by Oryzon Genomics

2 years ago
iadademstat, acute myeloid leukemia (AML), azacitidina+venetoclax, gilteritinib

Exploring the triple combination with venetoclax and azacitidine

Bellvitge participa en un ensayo clínico internacional que podría transformar el tratamiento de la amiloidosis cardíaca

by Hospital Universitari de Bellvitge

2 years ago
amiloidosis cardíaca por transtiretina (ATTR-CM), Vutrisiran

Sugieren que el fármaco Vutrisiran, un silenciador del RNA mensajero administrado de manera subcutánea cada tres meses, podría convertirse en un nuevo estándar de tratamiento para esta enfermedad ...

Merck administra cladribina comprimidos al primer paciente con miastenia grave generalizada en el ensayo de fase III MyClad

by Asebio

2 years ago
miastenia grave generalizada (gMG), cladribina

MyClad es un estudio global fase III que evalúa la eficacia y seguridad de cladribina comprimidos para el tratamiento de la miastenia grave generalizada (gMG, por sus siglas en inglés).

Aura Biosciences Reports Positive Phase 2 End of Study Results Evaluating Bel-sar as a First-Line Treatment for Early-Stage Choroidal Melanoma

by Ysios Capital

2 years ago
Aura Biosciences, choroidal melanoma (CM), bel-sar (AU-011)

Bel-sar Demonstrated 80% Tumor Control Rate, 90% Visual Acuity Preservation, and a Highly Favorable Safety Profile

The RESILIENCE trial: preventing heart injury caused by anticancer drugs

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

2 years ago
remote ischemic conditioning (RIC), Anthracycline cardiotoxicity, RESILIENCE

RESILIENCE is a clinical trial funded by the European Commission (H2020 Programme) that aims to reduce the prevalence of heart failure in cancer survivors

Investigational antibody-drug conjugate shows promising efficacy in patients with advanced endometrial or ovarian cancer

by VHIO

2 years ago
Datopotamab deruxtecan (Dato-DXd), endometrial or ovarian cancer, TROP2

The phase 2 multicenter TROPION-PanTumor study was designed to evaluate the efficacy of TROP2-directed antibody-drug conjugate datopotamab deruxtecan (Dato-DXd) as monotherapy and in combination with...

Vall d’Hebron Institute of Research (VHIR) participates in a Consortium to validate and scale-up the human skin production generated by a 3D bioprinter

by Vall d’Hebron

2 years ago
4D-Bioskin, 3D bioprinter

This project of personalized and regenerative medicine will carry out the first clinical trial in Spain to treat burns and skin wounds with bioprinted autologous human skin substitutes.

Research in Pitt-Hopkins at Sant Joan de Déu, a neurodevelopmental disorder

by Fundació Sant Joan de Déu

2 years ago
Pitt-Hopkins syndrome, TCF4 gene, MECP2 gene, Rett syndrome

Pitt-Hopkins syndrome is a rare genetic disorder, with an incidence of 1/11,000 to 1/41,000, caused by mutations in the TCF4 gene. This gene is crucial for the normal development of the nervous system...

Engrail Therapeutics Initiates ENX-104 Clinical Program for the Treatment of Major Depressive Disorder Characterized by Anhedonia

by Ysios Capital

2 years ago
ENX-104, anhedonia (aMDD), Engrail Therapeutics

The first-in-human Phase 1 clinical study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamic profile of ENX-104 in healthy volunteers