Latest Clinical trials biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

Neurona Doses First Patient in Phase 1/2 Trial of NRTX-1001 Cell Therapy in Adults with Drug-Resistant, Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

by Ysios Capital

1 year ago
Bilateral Mesial Temporal Lobe Epilepsy (MTLE), NRTX-1001 Cell Therapy

First patient received bilateral administration of NRTX-1001; no significant surgical complications or adverse events reported to date

New Inmunotherpay strategy in non-clear cell renal cell cancer

by VHIO

1 year ago
ipilimumab plus nivolumab, non-clear cell renal cell cancer

The phase 2 international multicenter SUNNIFORECAST study is the first prospective randomized trial evaluating dual immunotherapy with ipilimumab plus nivolumab against standard-of-care (SOC) tyrosine...

ORYZON announces submission of Phase III protocol to FDA to initiate PORTICO-2 trial of vafidemstat in Borderline Personality Disorder (BPD) patients

by Oryzon Genomics

PORTICO-2 designed to validate vafidemstat’s efficacy in reducing aggression in BPD patients

CNIO scientists develop test that predicts which patients will not respond to cancer chemotherapy

by CNIO - Centro Nacional de Investigaciones Oncológicas

1 year ago
chromosomal instability, Chemotherapy, platinum compounds, taxanes, and anthracyclines

The use of these biomarkers in clinical practice would allow for more effective treatments and the avoidance of side effects.

Problems and Solutions in ELISA assay validation

by Abyntek

1 year ago
ELISA assays

Validating this technique is key to obtaining reliable data, but the path is not always obstacle-free. From inconsistent results to issues with sensitivity or specificity, errors can arise at any stag...

ORYZON to host virtual KOL event on July 9, 2025

by Oryzon Genomics

1 year ago
Borderline Personality Disorder (BPD), vafidemstat

To discuss the unmet medical need in Borderline Personality Disorder (BPD) and the design of vafidemstat’s Phase III PORTICO-2 trial in BPD

Analytical Priorities in Drug Development: How Preclinical Data Shapes Regulatory Success

by AMSbiopharma

1 year ago
LC-MS/MS and UPLC-MS/MS Applications, Drug Development

Analytical method development in drug discovery refers to the process of designing, optimizing, and validating analytical techniques that can accurately characterize a drug candidate before it enters ...

An international study validates the efficacy of a drug in adults with neurofibromatosis type 1

by Hospital Universitari Germans Trias i Pujol

1 year ago
neurofibromatosis type 1, selumetinib

A clinical trial involving the Germans Trias i Pujol Research Institute and Hospital demonstrates that administering selumetinib reduces the tumour and the associated pain.

Antibodies for ex vivo models

by Abyntek

1 year ago
Antibodies

At Abyntek, they offer a solution that makes a real difference: antibodies formulated for in vivo use, now successfully applied in ex vivo systems such as organoids, 3D cultures, and organ-on-a-chip p...

El ayuno intermitente es tan eficaz para perder peso como las dietas convencionales

by Universitat Rovira i Virgili

1 year ago
ayuno intermitente

Un equipo investigador internacional con participación de la URV ha analizado el potencial de las dietas de ayuno intermitente para combatir la obesidad

Adding immunotherapy before and after surgery improves outcomes in head and neck cancer patients

by VHIO

1 year ago
KEYNOTE-689, pembrolizumab, immunotherapy

The phase 3 clinical trial KEYNOTE-689 shows that incorporating the monoclonal antibody pembrolizumab before and after surgery, alongside standard of care, improves event-free survival in patients wit...

Sant Pau Participates in One of the Most Relevant International Trials on the Discontinuation of Invasive Mechanical Ventilation in Critically Ill Patients

by Hospital de la Santa Creu i Sant Pau

1 year ago
proportional-assist ventilation (PAV+), pressure-support ventilation (PSV)

The study compares proportional-assist ventilation (PAV+) with pressure-support ventilation (PSV), with the goal of determining whether the former method could facilitate faster and less complicated w...