Lecanemab y los inicios de una nueva era en el tratamiento del Alzheimer

by Fundación Pasqual Maragall

En enero de 2023 el fármaco recibió la autorización del organismo regulador americano de alimentos y medicamentos, la Food and Drug Administration (FDA), por la vía de aprobación acelerada y, a p...

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ORYZON receives minutes from End-of-Phase II meeting with the FDA on the PORTICO-2 Phase III vafidemstat trial in Borderline Personality Disorder

by Oryzon Genomics

Oryzon Genomics announced today the receipt of the official meeting minutes from a recent End-of-Phase II meeting for vafidemstat in Borderline Personality Disorder (BPD) with the US Food and Drug Adm...

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El HUMV-IDIVAL participa en un tratamiento pionero en la enfermedad enfermedad injerto contra receptor crónica

by Instituto de Investigación Marqués de Valdecilla

El estudio ha investigado la eficacia del axatilimab, un nuevo anticuerpo monoclonal humanizado que actúa inhibiendo el receptor CSFR1, presente en macrófagos y monocitos, células implicadas en el ...

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Un fármaco contra el cáncer de médula ósea demuestra su eficacia en el tratamiento de un raro trastorno sanguíneo

by Revista Genética Médica

Hallan pruebas suficientes de un fármaco utilizado para tratar el cáncer de médula ósea y el sarcoma de Kaposi que es seguro y eficaz en el tratamiento de la telangiectasia hemorrágica hereditari...

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CNIO researchers propose a new treatment for brain metastasis based on immunotherapy

by CNIO - Centro Nacional de Investigaciones Oncológicas

CNIO researchers have discovered that cancer perverts certain brain cells, the astrocytes, and causes them to produce a protein that works in favour of the tumour. A drug, silibinin, inhibits this pro...

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Añadir inmunoterapia aumenta supervivencia en cáncer de vejiga

by VHIO

Demuestran por primera vez los beneficios de una estrategia basada en añadir el fármaco de inmunoterapia durvalumab a la quimioterapia neoadyuvante que se administra antes de la cirugía para extirp...

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The Use of Biomarkers in Alzheimer’s Faces Challenges Like Standardization and Variability in Real Patients

by Hospital de la Santa Creu i Sant Pau

Highlight the main technical, clinical, and regulatory challenges currently faced when integrating these biomarkers into daily clinical practice and adapting them to different healthcare settings. The...

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Exploring predictive biomarkers in metastatic colorectal cancer

by VHIO

This analysis explores biological factors that could influence how patients with metastatic colorectal cancer with BRAF V600E mutation respond or develop resistance to targeted therapy.

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AEMPS autoriza su ensayo con secretomas dirigidos para tratar la tormenta de citoquinas

by Peaches Biotech

EL PRS® CK-Storm será el primero de una serie de medicamentos, basados en el uso de secretomas dirigidos, para ayudarán a combatir diferentes tipos de patologías autoinmunes.

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Adcendo Announces US FDA Clearance of IND Application for Phase I/II First-in-Human ADCElerate-01 Trial of ADCE-D01 (uPARAP Receptor Targeting ADC) Trial in Patients with Metastatic and/or Unresectable Soft Tissue Sarcoma (STS)

by Ysios Capital

The Phase I/II ADCElerate-01 trial is designed to evaluate the safety, pharmacokinetics, and preliminary efficacy of ADCE-D01 as a monotherapy in patients with metastatic and/or unresectable STS

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Updating the Evidence on Drugs to Prevent Malaria in HIV-Positive Pregnant Women

by ISGlobal - Instituto de Salud Global de Barcelona

A Cochrane review led by ISGlobal researchers updates the evidence on interventions for malaria and HIV during pregnancy

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Interview David Segarra – CEO and Co-Founder of aptaTargets

by GENESIS Biomed

David Segarra: “ApToll is an immune modulator to treat ischaemic stroke in the acute phase. We have successfully completed Phase 2a and will soon conduct Phase 2b. We are also testing ApToll for oth...

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