ORYZON announces journal publication of final Phase IIa REIMAGINE results with vafidemstat in Psychiatry and Clinical Neurosciences

by Oryzon Genomics

The Phase IIa study REIMAGINE evaluated the safety and preliminary efficacy of vafidemstat in agitation/aggression in borderline personality disorder (BPD), attention-deficit/hyperactivity disorder (A...

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Una nueva opción terapéutica mejora la supervivencia en pacientes con cáncer de próstata metastático

by Vall d’Hebron

Los resultados del ensayo de fase III TALAPRO-2, en que participa el VHIO, demuestran que la combinación de talazoparib más enzalutamida frente al tratamiento estándar de enzalutamida mejora signif...

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Una paciente con neuroblastoma lleva 18 años en remisión tras una terapia con CAR-T

by Agencia Sinc

Este tumor pediátrico poco frecuente tiene una alta tasa de recaída con los tratamientos convencionales. Según los autores del estudio publicado en Nature Medicine, se trata de la remisión más p...

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Recruitment of Patients for Clinical Trials: The Importance of Thinking About the Patient from the Start

by Sermes CRO

Recruiting patients to participate in clinical trials can be a complex and costly process for clinical research promoters. However, considering their needs, emotional situation, scientific understandi...

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Investigadores del IMIBIC identifican inflamación sistémica en vitíligo y posibles nuevas vías terapéuticas para esta enfermedad

by Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)

Personal investigador del Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC) y el Hospital Universitario Reina Sofía (HURS), ha identificado, por primera vez, la existencia de pa...

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MYC: from undruggable target to the first cancer clinical trials

by VHIO

The MYC oncogene is deregulated in approximately 70% of human cancers and is associated with aggressive disease and cancer drug resistance, making it one of the most sought-after targets in oncology. ...

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AECC funds new paths to thwart cancer’s deadliest moves

by Centre for Genomic Regulation

Two researchers at the Centre for Genomic Regulation (CRG) in Barcelona are tackling an urgent question: how can we stop cancer before it spreads? Thanks to new grants from the Spanish Association Aga...

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Clinical trial on personalized physical exercise for elderly cancer patients shows promising preliminary results

by Vall d’Hebron

It is part of the PROFIT Project (Personalizing the Approach to Frail Oncology Patients through Assessment and Individualized Intervention), an innovative initiative focused on providing comprehensive...

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Neurona Unveils Phase 3 EPIC Study for NRTX-1001 Cell Therapy in Epilepsy

by Ysios Capital

Based on alignment gained with FDA under the Regenerative Medicine Advanced Therapy (RMAT) designation, Neurona plans to conduct the Phase 3 EPIC (EPIlepsy Cell therapy) trial as the primary basis for...

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El Hospital público 12 de Octubre lidera un ensayo para demostrar la efectividad de un tratamiento en adultos con una enfermedad ultrarrara

by Hospital Universitario 12 de Octubre

Está en fases avanzadas de desarrollo clínico, pero solo para casos cuyos síntomas se hayan iniciado antes de los 12 años

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Biomedicamento contra el síndrome inflamatorio derivado de infecciones pulmonares graves

by Peaches Biotech

Peaches Biotech está investigando con su ensayo piloto, en fase I-II, del PRS® CK STORM contra la tormenta de citoquinas que se da en una cantidad significativa de casos en personas afectadas por vi...

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Adcendo ApS Announces U.S. FDA Clearance of IND Application for Phase I Tiffany-01 Trial of ADCE-T02

by Ysios Capital

ADCE-T02 is a potential first-in-class Topoisomerase I inhibitor-based antibody-drug conjugate (ADC) targeting tissue factor, a validated ADC target overexpressed in multiple solid tumors

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