Descubren una potencial diana terapéutica que aumenta los niveles de FGF21 para el tratamiento de enfermedades metabólicas

by CIBERDEM - Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas

Esta investigación ha probado que el tratamiento con fármacos capaces de activar la HRI (heme-regulated inhibitor eiF2alpha kinase) aumentan los niveles de FGF21 causando una reducción de la intole...

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Ceftazidima-avibactam una nueva opción para Pseudomonas multirresistente

by Instituto de Investigación Marqués de Valdecilla

Pseudomonas aeruginosa es uno de los microorganismos con mayores problemas de multirresistencia en la práctica clínica causante de un gran número de infecciones intrahospitalarias. A menudo las opc...

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The potential of drug repurposing: Laura Soucek and co-authors consider the case of kinase inhibitor ibrutinib

by Vall d’Hebron

Emerging data from various mouse models of cancer also suggest that BTK inhibition in other cell types using ibrutinib can be extended beyond pancreatic cancer for the effective treatment of a spectru...

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Did you know that the testing of drugs for the treatment of Alzheimer's disease requires in vivo models?

by Fundació Bosch i Gimpera

The design and testing of drugs potentially useful in the treatment of Alzheimer's disease require models that reproduce the etiopathogenic factors responsible for the disease

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Exploring mechanisms of resistance against ER+ and BRCA1 breast cancer therapies

by Vall d’Hebron

Various research lines led by VHIO aim at better deciphering how tumor cells acquire resistance to anticancer agents including palbociclib and treatments inducing DNA damage. The expression of partial...

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La SEMI y Farmaindustria afianzan su colaboración con un convenio que refuerza la transparencia

by Farmaindustria

El acuerdo tiene como objetivo contribuir, a través de la transparencia en la relación de la industria innovadora con los profesionales y organizaciones sanitarias, a reforzar la credibilidad y la c...

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The effectiveness of the obeticholic acid to treat primary biliary cholangitis has been proven

by Vall d’Hebron

​A study recently published in the prestigious journal The New England Journal of Medicine, of which has been co-author Dr. Victor Vargas, head of the Section of the Haepatology Service of the Vall ...

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New strategy may help prevent kidney failure in patients with diabetes

by Fundación Jiménez Díaz

​A new strategy designed by researchers at the Jiménez Díaz Foundation University Hospital-Quirónsalud Group may help halt the progression of kidney disease in patients with diabetes. The approac...

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Building molecular complexity from scratch

by IRB Barcelona - Instituto de Investigación Biomédica

Xavier Verdaguer—associate researcher in the Asymmetric Synthesis Lab, headed by Antoni Riera—writes a Science Perspectives article on an study by Chuang et al. that describes a new method for the...

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La Unidad de Ensayos Clínicos Fase I de INCLIVA tiene en marcha 21 ensayos con medicamentos oncológicos experimentales

by INCLIVA

Es una de las Unidades más activas que existen en España, y la única en la Comunidad Valenciana. Se ha convertido en un referente internacional al colaborar activamente con los mejores hospitales d...

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Euskadi acoge ensayos con un prometedor fármaco contra el alzheimer

by BioCruces Health Research Institute

Un estudio sobre un fármaco para tratar el alzheimer que aparece en la portada de la revista Nature tiene que ser un tema interesante, aunque la comunidad científica sea siempre muy cauta a la hora ...

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New drug discovery company in the area of rare diseases

by CIC bioGUNE

The new company, Atlas Molecular Pharma, aims to develop a technology capable of detecting molecules which stabilize proteins involved in the development of certain rare diseases. The venture capital ...

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