El CIC incorpora tecnologías de frontera para entender el origen de las metástasis o las recaídas en los tratamientos oncológicos

by Centro de Investigación del Cáncer

Incluir las técnicas de transcriptómica espacial y de secuenciación de célula única permitirá analizar interacciones de las células tumorales entre sí, o con otras células normales para expli...

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El CSIC descubre un nuevo mecanismo que permite a las células degradar proteínas sin consumir energía

by CSIC - Centro Superior de Investigaciones Científicas

La investigación del CNB sugiere que esta vía podría inspirar nuevas estrategias clínicas para evitar la acumulación de las proteínas tóxicas asociadas a trastornos neurodegenerativos

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El alcohol altera la expresión de genes clave incluso tras consumos esporádicos

by Instituto de Investigación Biomédica de Salamanca - IBSAL

El consumo excesivo de alcohol, tanto crónico como ocasional, provoca alteraciones en la glucólisis, la principal vía metabólica para producir energía, lo que podría sugerir una conexión entre ...

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Vall d’Hebron research describes a mechanism by which cardiac ageing promotes heart failure

by Vall d’Hebron

The accumulation of metabolic products within cardiac cells alters their function and accelerates the deterioration of heart tissue with age.

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Metabolomics and lipidomics in drug discovery and development: analytical approaches for biomarker discovery and preclinical research

by AMSbiopharma

The search for safer, more effective medicines increasingly depends on understanding how biological systems respond to disease, genetic variation, and therapeutic interventions at the molecular level....

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Mutations in the 'translators' of the human cell alter the reading of the genetic code in cancer and ageing

by IRB Barcelona - Instituto de Investigación Biomédica

A study by IRB Barcelona reveals that transfer RNA (tRNA) genes accumulate mutations at a frequency up to nine times higher than average

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A new experimental strategy enables the elimination of proteins involved in pathological processes

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

It has been developed a strategy that enables the forced elimination of proteins that help tumors survive chemotherapy. This finding opens a new avenue to tackle resistance to cancer treatments, one o...

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Decoding cancer cell communication to improve pancreatic cancer treatment

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Cancer cells do not act alone. Through complex communication networks and signalling pathways, tumour cells and their microenvironment coordinate adaptive responses that drive drug resistance. Underst...

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A new study names part of the human genome

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

An international study published in the journal Nature has designated a subset of the so-called dark proteins - proteins with no known function - as peptideins. Characterising them opens the door to s...

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Un nuevo mapa molecular de poblaciones humanas abre vías para la medicina de precisión

by Instituto de Investigación Biomédica de Salamanca - IBSAL

El estudio analiza datos de cientos de personas sanas de distintos países y orígenes. Su objetivo es comprender cómo factores como la genética, la geografía, la dieta influyen en el estado del si...

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European project BT4ChildLC advances precision medicine for childhood liver cancer

by Hospital Universitari Germans Trias i Pujol

The European project BT4ChildLC, led by the Germans Trias i Pujol Research Institute (IGTP), has laid the foundations for more precise diagnosis and treatment strategies for childhood liver cancer by ...

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