Latest Scientific publications biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

A New Weak Spot Found in the Malaria Parasite

by ISGlobal - Instituto de Salud Global de Barcelona

1 year ago
Plasmodium falciparum, PfGNA1, glycosylphosphatidylinositols (GPIs), hexosamine

Targeting a key metabolic step in 'P. falciparum' offers hope for developing new treatments that don’t harm human cells

Identifican alteraciones del microbioma intestinal en pacientes recién diagnosticados de EII antes del tratamiento

by CIBEREHD-Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

12 months ago
enfermedad inflamatoria intestinal (EII), metagenómica tipo shotgun

El uso de secuenciación metagenómica tipo shotgun permite detectar bacterias, virus, hongos y otros microorganismos no bacterianos, superando las limitaciones del enfoque clásico del estudio del AR...

CNAG launches Pheno-Ranker, a software to compare phenotypic data and advance rare disease research

by Parc Científic de Barcelona

12 months ago
rare disease, Pheno-Ranker

It has been developed Pheno-Ranker, an open-source toolkit that transforms complex phenotypic data into actionable information, accelerating the discovery of diagnoses for rare diseases and facilitati...

A New Blood Biomarker Predicts the Progression of Alzheimer’s Disease Even in Its Earliest Stages

by Hospital de la Santa Creu i Sant Pau

12 months ago
plasma biomarker p-tau217, Alzheimer

A team of researchers at the Sant Pau Research Institute (IR Sant Pau) has demonstrated that the plasma biomarker p-tau217, obtained through a simple blood test, can predict the clinical progression o...

An international study led by CIC bioGUNE identifies key mechanisms of an enzyme involved in a rare metabolic disease

by CIC bioGUNE

12 months ago
classical homocystinuria

The research, published in The FEBS Journal, improves understanding of classical homocystinuria, a hereditary metabolic disorder, and proposes new potential therapeutic approaches.

Un nuevo estudio reduce errores en imágenes médicas con una técnica innovadora basada en IA

by Bionand

12 months ago
IA MedSAM, Test-Time Augmentation (TTA)

Un nuevo estudio reduce errores en imágenes médicas con una técnica innovadora basada en IA.

Novel drug combination metastatic prostate cancer

by VHIO

12 months ago
metastatic prostate cancer, cabozantinib, atezolizumab, androgen receptor pathway inhibitor (ARPI)

The phase 3, multi-center, open-label, randomized CONTACT-02 trial, was designed to evaluate the safety and efficacy of cabozantinib, a tyrosine kinase inhibitor (TKI), combined with immune checkpoint...

Activar una vía de defensa mitocondrial revierte el daño celular en modelos de encefalopatía etilmalónica

by Universidad Pablo de Olavide, de Sevilla

12 months ago
respuesta mitocondrial a proteínas mal plegadas (mtUPR), encefalopatía etilmalónica (EE)

El grupo de investigación ‘Desarrollo y enfermedades musculares’ del Centro Andaluz de Biología del Desarrollo logra corregir alteraciones fisiopatológicas en modelos celulares de esta grave en...

La lactancia materna protege al bebé frente a la resistencia a los antibióticos a través de la microbiota intestinal

by CSIC - Centro Superior de Investigaciones Científicas

12 months ago
leche materna, bacterias Bifidobacterium, resistoma

La alimentación exclusiva con leche materna durante el primer mes de vida reduce la presencia de microorganismos resistentes a estos fármacos, según un estudio publicado en ‘Nature Communications...

Cognitive impairment in lung cancer, an undervalued disorder with new approaches and treatment perspectives

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

12 months ago
Cognitive impairment, small cell lung cancer (SCLC), brain-derived neurotrophic factor (BDNF)

Researchers have managed to identify biomarkers for cognitive impairment in this group of patients that could help in its diagnosis.

New approach to decoding mutational signatures improves prediction of prognosis in ovarian cancer

by IRB Barcelona - Instituto de Investigación Biomédica

12 months ago
mutational signatures, ovarian cancer

Researchers at IRB Barcelona and BRIC Copenhagen present a method that combines two types of mutations to better identify DNA repair problems.

OneChain Immunotherapeutics presents OC-1d, a new cell therapy against leukemia that shows high efficacy and safety in the laboratory

by OneChain Immunotherapeutics

12 months ago
T-cell acute lymphoblastic leukemia (T-ALL), OC-1d, proteins CD1a and CCR9

It has been developed a new cell therapy based on CAR-T cells designed to simultaneously target two specific markers of T-cell acute lymphoblastic leukemia (T-ALL): the proteins CD1a and CCR9.