La inhibición de la proteína inflamatoria IL-11 aumenta la esperanza de vida en ratones

by Revista Genética Médica

La inhibición de la proteína inflamatoria interleucina 11 (IL-11) mejora la salud y aumenta hasta un 25% la esperanza de vida en ratones.

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Mechanisms of action of lithium in bipolar disorder and other neurological diseases reviewed

by Fundació Clínic per a la Recerca Biomèdica

Researchers at the Clínic-IDIBAPS have prepared a review article on the biology, mechanism of action, pharmacology and toxicology of lithium.

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Un antioxidante celular favorece el crecimiento de los tumores linfáticos y su resistencia terapéutica

by CSIC - Centro Superior de Investigaciones Científicas

Un estudio liderado por el CSIC identifica que el glutatión, uno de los antioxidantes más abundantes en las células, favorece la supervivencia de las células iniciadoras de los tumores linfáticos...

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Viral defence protein speeds up female stem cell production

by Centre for Genomic Regulation

​Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice. This discovery that has the potent...

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Validation of the efficacy of a treatment for migraine in real clinical practice

by Fundació Clínic per a la Recerca Biomèdica

Researchers at the Clínic-IDIBAPS coordinated a study that highlights the efficacy of migraine treatment with a monoclonal antibody, galcanezumab, in routine clinical practice.

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'Detective’ Algorithm Predicts Best Drugs for Genetic Disorders and Cancer

by IRB Barcelona - Instituto de Investigación Biomédica

RTDetective is a new computational model which can predict which drugs will be most effective in treating diseases caused by premature stop codons, or ‘stop signs’ that appear in DNA and result in...

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Identifican dos compuestos que orientan nuevos tratamientos para un tipo de leucemia

by CIMA - Centro de Investigación Médica Aplicada

Investigadores del Cima y de la Clínica Universidad de Navarra demuestran que dos potentes inhibidores, CM-444 y CM-1758, tienen capacidad para promover la diferenciación mieloide en todos los subti...

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Por qué el ejercicio físico estimula el deseo de mantenerse activo: revelan la relación molecular entre el músculo y el cerebro

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

Los músculos activan la p38γ a causa del ejercicio y secretan una cantidad mayor de la proteína interleuquina 15 (IL-15), que tiene un efecto directo sobre la parte de la corteza cerebral que contr...

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Approved by EMA, novel oral AKT inhibitor in combination improves clinical outcomes and prolongs quality of life in patients with advanced HR+/HER2- breast cancer

by VHIO

The European Medicines Agency (EMA) recently approved the combination of novel AKT inhibitor capivasertib with fulvestrant for patients with hormone receptor (HR)-positive, HER2-negative advanced or m...

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Eficacia y elección del tratamiento para la esofagitis eosinofílica en la edad pediátrica

by CIBEREHD-Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

Un estudio ha evaluado los factores que afectan a la elección de la primera línea de tratamiento y a su eficacia en niños y adolescentes con esofagitis eosinofílica (EEo).

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AI Spots Cancer and Viral Infections at Nanoscale Precision

by Centre for Genomic Regulation

It has been developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells. The findings, publishe...

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Different hierarchical reconfigurations in the brain by psilocybin and escitalopram for depression

by UPF - Universitat Pompeu Fabra

Two pharmacological treatments used for depression affect the brain in completely different ways, shedding light on how the depressed brain gets rebalanced, according to a paper published in the journ...

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