Amino acids play a key role in how cells respond to drugs

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like bricks that communicate with each other within a structure. In this way, th...

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An aggressive childhood cancer case opens new avenues for advanced cell therapies

by IRB Barcelona - Instituto de Investigación Biomédica

After receiving chemotherapy and radiotherapy, the patient also began immunotherapy with immune checkpoint inhibitors (ICI), a treatment that boosts the ability of lymphocytes to recognise and combat ...

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Top Spanish hospitals adopt the MAF Test to improve breast cancer treatment

by IRB Barcelona - Instituto de Investigación Biomédica

This groundbreaking test helps oncologists determine which breast cancer patients should be treated with bisphosphonates to improve their prognosis and survival.

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UB-IDIBELL study identifies key neurophysiological mechanism in human memory formation

by Universitat de Barcelona

It has been identified, for the first time in humans, and in a realistic environment, a key neurophysiological mechanism in memory formation: ripple-type brain waves —high-frequency electrical oscil...

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Study discovers how brucellosis bacterium tricks the immune system

by Universidad de Navarra

The research, published in the journal Nature Communications, identifies an area of the abdomen as a hiding place for the bacteria, which could explain why the disease becomes chronic.

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New insights into heart scar tissue could improve treatment after heart attacks

by Hospital Universitari Germans Trias i Pujol

The group found an association between specific electrical patterns and structural characteristics of the scar, offering a new approach that may guide more targeted and effective treatments for arrhyt...

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Desarrollo de un método innovador para estudiar contactos entre orgánulos celulares sin alterar su función

by Professional Newco

Un equipo internacional presenta en la revista PLOS Biology una técnica innovadora para visualizar y cuantificar los puntos de contacto entre el retículo endoplásmico y otros orgánulos celulares, ...

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La molécula AMPc, una diana terapéutica para recuperar la capacidad locomotora tras una lesión medular

by Universidad Pablo de Olavide, de Sevilla

Investigadores de la Universidad Pablo de Olavide colaboran en un estudio pionero liderado por el Centro de Investigación Príncipe Felipe que acelera la recuperación en animales tras una lesión me...

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A gut microbiota metabolite linked to atherosclerosis could revolutionise diagnosis and treatment

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

A new study led by the CNIC has identified imidazole propionate (ImP), a metabolite produced by gut bacteria, as a driver of atherosclerosis— as a driver of atherosclerosis, the disease behind most ...

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Descubren un mecanismo que controla el sistema de alarma celular durante la replicación del material genético

by CSIC - Centro Superior de Investigaciones Científicas

Investigadores del Centro de Biología Molecular Severo Ochoa (CBM, CSIC-UAM) han identificado un mecanismo que permite a las células copiar su ADN de manera segura y ordenada. Esto permite comprende...

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A Bellvitge study analyzes the clinical impact of amoxicillin resistance on invasive pneumococcal pneumonia

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

The study shows that resistant strains persist despite conjugate vaccines and warns of worse outcomes in people with a poor prognosis treated with amoxicillin.

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Durvalumab With Novel Immunotherapies Improves Progression in Locally Advanced Lung Cancer

by Hospital de la Santa Creu i Sant Pau

Treatment with durvalumab, a PD-L1 inhibitor monoclonal antibody, has become established recently as the standard therapy for patients with unresectable stage III non-small cell lung cancer (NSCLC) wh...

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