Latest Scientific publications biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

The role of oxidative stress in the progression of Alzheimer's disease is shown to affect only the cellular level

by IRB Lleida. Institut de Recerca Biomèdica

10 months ago
oxidative stress, Alzheimer

It has been has shown that the role of oxidative stress in the progression of Alzheimer's disease affects only at the cellular level and instead, damage in extracellular fluids, such as plasma and cer...

Chagas Disease is Also Underdiagnosed in Spain

by ISGlobal - Instituto de Salud Global de Barcelona

10 months ago
Chagas disease

Although the vector that transmits the parasite (the kissing bug) is endemic in 21 Latin American countries, the parasite has spread globally due to migratory flows.

LRP1-based immunotherapy would reduce remodeling of the cardiac extracellular matrix due to cholesterol accumulation

by Hospital de la Santa Creu i Sant Pau

10 months ago
cardiac extracellular matrix (ECM), LRP1 immunotherapy, anti-P3 antibodies, cholesterol

It has been revealed that LRP1-based immunotherapy reduces cardiac extracellular matrix (ECM) remodeling induced by intracellular accumulation of esterified cholesterol in cardiomyocytes.

An already approved drug could help eliminate resistance to the most effective treatment against metastatic breast cancer

by CNIO - Centro Nacional de Investigaciones Oncológicas

10 months ago
metastatic breast cancer, uminal breast cancer, RANK protein, denosumab, inhibitors of CDK4/6, osteoporosis

An international study with CNIO participation has discovered that RANK protein contributes to this resistance and that an already approved drug to treat osteoporosis blocks the protein

Alert about the sustained deterioration of marine ecosystems in southern Spain

by Universidad Autónoma de Madrid

9 months ago
marine ecosystems, ecosystem approach

The marine biodiversity of the Gulf of Cádiz and the Alborán Sea shows a worrying decline over the last three decades, according to a study led by the Autonomous University of Madrid (UAM). The resu...

A combination therapy, new option for patients with advanced urothelial cancer who cannot receive conventional chemotherapy

by Hospital de la Santa Creu i Sant Pau

9 months ago
advanced urothelial cancer, enfortumab vedotin and pembrolizumab

Researcher has been able to verify that the combination of two drugs, enfortumab vedotin and pembrolizumab, which had previously shown benefits in survival in second-line treatment and in cases of adv...

Investigadores de INCLIVA estudian los posibles efectos adversos de la presencia de citomegalovirus (CMV) en la sangre de pacientes receptores de terapia CAR-T

by INCLIVA

9 months ago
citomegalovirus (CMV), terapia CAR-T

Investigadores del Instituto de Investigación Sanitaria INCLIVA, del Hospital Clínico de València, han desarrollado un estudio para analizar y evitar los posibles efectos adversos derivados de la p...

Un equipo del CSIC crea una herramienta bioinformática para obtener genomas de calidad

by CSIC - Centro Superior de Investigaciones Científicas

9 months ago
ILRA

Han creado ILRA, una herramienta bioinformática con un gran potencial para generar genomas de alta calidad en contextos especialmente problemáticos, como en el caso de especies con genomas complejos...

Consumir menos alimentos ultraprocesados puede mejorar la sostenibilidad medioambiental

by CIBERobn- Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición

9 months ago
alimentos ultraprocesados, dieta mediterranea

Se descubrió que el consumo de alimentos ultraprocesados también está asociado con un mayor impacto medioambiental en términos de emisiones de gases de efecto invernadero, uso de agua y uso de ene...

Los astrocitos utilizan los ácidos grasos para mantener las capacidades cognitivas

by DiCYT - Agencia Iberoamericana para la Difusión de la Ciencia y la Tecnología

9 months ago
astrocitos, especies reactivas de oxígeno (ROS)

En su mayor parte los componentes primordiales de las grasas “van destinados a que la cadena respiratoria de la mitocondria de estas células cerebrales se organice para producir especies reactivas ...

Researchers outline the mechanisms that control the conversion between fetal and adult intestinal stem cells

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

9 months ago
transcription factors, SMARCA4 and SMARCC1, YAP protein

Using different molecular approaches, they demonstrate the utility of organoid models to identify the factors that regulate cell fate and reveal that the transcription factors SMARCA4 and SMARCC1 prev...

Una mutación en el gen DOCK11 explica un trastorno raro en la regulación del sistema inmunitario

by Fundació Sant Joan de Déu

9 months ago
gen DOCK11

Investigadores del Institut de Recerca Sant Joan de Déu · Hospital Sant Joan de Déu Barcelona participan en un estudio internacional, publicado en la prestigiosa revista científica New England ...