Bellvitge identifica por qué un fármaco común contra la diabetes tipo II puede perder eficacia

by Hospital Universitari de Bellvitge

Un equipo investigador del Hospital de Bellvitge, el IDIBELL, la Universitat de Barcelona (UB) y el CIBERDEM ha descubierto que el uso crónico de la glibenclamida, un fármaco de la familia de las su...

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First evidence of a ‘nearly universal’ pharmacological chaperone for rare disease

by Centre for Genomic Regulation

A study published today in Nature Structural & Molecular Biology is the first time researchers have shown evidence that a single drug, already licensed for medical use, can stabilise nearly all mutate...

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A group of genes could anticipate the response to a key breast cancer treatment

by IrsiCaixa

The KIMA genomic signature identifies patients with HR+/HER2– breast cancer who have a lower response to CDK4/6 inhibitors, enabling more personalized treatments

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UPF researchers design a new experimental screening system to identify peptides with therapeutic potential

by UPF - Universitat Pompeu Fabra

The research has been carried out in conjunction with Stanford University and has enabled designing a screening system to identify extremely selective peptides with therapeutic potential that minimize...

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El desarrollo de una terapia génica ‘suicida’ abre nuevas opciones contra el sarcoma de Ewing, un cáncer infantil raro

by CIBERER - Centro de Investigación Biomédica en Red de Enfermedades Raras

Cuando las células de sarcoma de Ewing son infectadas por el adenovirus terapéutico, estas expresan el gen ‘suicida’ HSV-TK. Este gen es inocuo, pero cuando se combina con la prodroga ganciclovi...

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Un estudio internacional confirma el uso del biomarcador p-tau217 en sangre para detectar el Alzheimer en fases iniciales

by Fundación Pasqual Maragall

Este biomarcador permite detectar la presencia de depósitos de beta amiloide, patología clave en el desarrollo de la enfermedad, en personas sin deterioro cognitivo

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Descubren un nuevo antiviral contra el herpes simple que vence la resistencia a los tratamientos actuales

by CSIC - Centro Superior de Investigaciones Científicas

Este nuevo candidato, aún es fase experimental, está inspirado en un antigripal en uso y ataca un proceso clave de la propagación del virus en el organismo

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Un nuevo algoritmo permite identificar con mayor precisión la flexibilidad en la estructura 3D de las proteínas

by CSIC - Centro Superior de Investigaciones Científicas

El sistema, diseñado por científicos del CNB-CSIC, aborda el desafío de captar las transiciones del movimiento de las macromoléculas biológicas y sus estructuras mediante IA

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A key gene could help predict the most aggressive form of prostate cancer

by CIC bioGUNE

The study, published in Molecular Oncology, reveals that the gene TCF19 plays a critical role in prostate cancer progression, tumor growth, and metastatic spread, highlighting its potential as a progn...

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Women With Familial Hypercholesterolemia Have a Significantly Lower Cardiovascular Risk Than Men

by Hospital de la Santa Creu i Sant Pau

The findings are conclusive. Over the follow-up period, women with FH showed a significantly lower risk of cardiovascular events compared to men. Moreover, when these events did occur, they did so at ...

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Genetic mechanisms revealed that allow poplars to survive severe droughts

by Centro de Biotecnología y Genómica de Plantas CBGP

It was known that trees could survive extreme water shortages thanks to their ability to produce more numerous and smaller vessels, but the molecular mechanisms underlying this response were unknown. ...

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Innovative non-invasive method for diagnosing cardiac arrhythmias

by Universitat Politècnica de València

The new method developed by the UPV and Corify Care S.L. achieves much higher accuracy than current non-invasive techniques, with up to an 80% reduction in errors

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