Descubren un nuevo antiviral contra el herpes simple que vence la resistencia a los tratamientos actuales

by CSIC - Centro Superior de Investigaciones Científicas

Este nuevo candidato, aún es fase experimental, está inspirado en un antigripal en uso y ataca un proceso clave de la propagación del virus en el organismo

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Un estudio internacional confirma el uso del biomarcador p-tau217 en sangre para detectar el Alzheimer en fases iniciales

by Fundación Pasqual Maragall

Este biomarcador permite detectar la presencia de depósitos de beta amiloide, patología clave en el desarrollo de la enfermedad, en personas sin deterioro cognitivo

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El desarrollo de una terapia génica ‘suicida’ abre nuevas opciones contra el sarcoma de Ewing, un cáncer infantil raro

by CIBERER - Centro de Investigación Biomédica en Red de Enfermedades Raras

Cuando las células de sarcoma de Ewing son infectadas por el adenovirus terapéutico, estas expresan el gen ‘suicida’ HSV-TK. Este gen es inocuo, pero cuando se combina con la prodroga ganciclovi...

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UPF researchers design a new experimental screening system to identify peptides with therapeutic potential

by UPF - Universitat Pompeu Fabra

The research has been carried out in conjunction with Stanford University and has enabled designing a screening system to identify extremely selective peptides with therapeutic potential that minimize...

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An IDIBAPS project receives one of the CaixaImpulse grants to improve cell therapies against solid tumours

by IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer

"La Caixa" Foundation will allocate €150,000 to the project led by Alba Rodríguez, from the IDIBAPS Cellular Immunotherapies for Cancer research group. It involves a study that aims to develop a ne...

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New arginine-based surfactants: a sustainable alternative with high antimicrobial efficacy

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

It has been developed a new family of cationic surfactants derived from arginine. These compounds stand out for their high antimicrobial efficacy, their ability to eradicate resistant biofilms, and th...

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Integrated DNA Technologies Launches New Enhancer Protein to Accelerate CRISPR-based Therapies from Translational Research to Clinical Breakthrough

by Integrated DNA Technologies

Research grade recombinant protein expands toolkit of available CRISPR nucleases and increases efficiency of homology-directed repair (HDR) to enable more precise genome modifications

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Critical Quality Attributes (CQAs) in Biologics Manufacturing: Why They Matter

by 53Biologics

At 53Biologics, they see CQAs as the blueprint of product quality. By identifying them early and controlling them consistently, biotech companies can navigate development more smoothly, avoid costly d...

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Bellvitge identifica por qué un fármaco común contra la diabetes tipo II puede perder eficacia

by Hospital Universitari de Bellvitge

Un equipo investigador del Hospital de Bellvitge, el IDIBELL, la Universitat de Barcelona (UB) y el CIBERDEM ha descubierto que el uso crónico de la glibenclamida, un fármaco de la familia de las su...

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High-fat diets modify genes that differentiate between sexes in key metabolic organs

by Fundació Clínic per a la Recerca Biomèdica

The research team observed that in mice fed high-fat diets, the males showed more severe metabolic impairments, despite the fact that both sexes developed a similar amount of body fat. By analysing th...

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First evidence of a ‘nearly universal’ pharmacological chaperone for rare disease

by Centre for Genomic Regulation

A study published today in Nature Structural & Molecular Biology is the first time researchers have shown evidence that a single drug, already licensed for medical use, can stabilise nearly all mutate...

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The CaixaImpulse programme funds a UB project to improve autism treatment

by Universitat de Barcelona

The focus is on how genes are regulated in the brain, a process that plays a key role in the development of autism. As a result, the team has designed a drug that works differently from current treatm...

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