Latest biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

Investigadores del CIC abordan nuevas vías para profundizar en los mecanismos de acción de los fármacos contra el cáncer

by Professional Newco

6 months ago
inhibidores MEK, Nilotinib, gen de fusión BCR-ABL1

El amplio mapa desarrollado de fármacos y genes diana, y el método innovador (denominado "farmaco-genómica") representan una herramienta prometedora para acelerar la identificación de nuevas diana...

Un estudio revela que el cuerpo emplea sensores distintos para detectar el frío en la piel y en los órganos internos

by CSIC - Centro Superior de Investigaciones Científicas

6 months ago
homeostasis térmica, canal iónico TRPM8, TRPA1

Un equipo liderado por el IN-CSIC-UMH ha comprobado en modelos animales que los mecanismos moleculares de detección del frío no son uniformes en todo el cuerpo

High-temperature steam hose: essential features and safety standards

by Tecno Products

6 months ago
High-temperature steam hoses

High-temperature steam hoses are critical components in numerous industrial processes where steam needs to be transported at high pressures and temperatures. Their specialized design ensures thermal r...

Implementation of UPLC‑MS/MS workflows in peptide therapeutics: from method development to regulatory submission

by AMSbiopharma

6 months ago
Ultra-High Performance Liquid Chromatography (UPLC), mass spectrometry, LC-MS/MS, peptide therapeutic

The integration of Ultra-High Performance Liquid Chromatography (UPLC) with tandem mass spectrometry has proven essential for accurate quantification and characterization. This technical advancement r...

Regulatory compliance: how CROs keep clinical trials aligned with regulations

by Sermes CRO

6 months ago
Regulatory compliance, CROs

What happens when a clinical trial fails to comply with regulations? Fines, delays, and loss of credibility are just the tip of the iceberg. In a sector where patient safety and scientific integrity a...

The urban environment during pregnancy influences the risk of wheezing and respiratory infections in early childhood

by ISGlobal - Instituto de Salud Global de Barcelona

6 months ago
urban exposome, wheezing and respiratory infections

Green spaces, air quality, temperature and the presence of pets are among the factors that influence children’s respiratory health

New Neuropsychological Reference Standards Enable Earlier Detection of One in Five Incipient Alzheimer’s Disease Cases

by Hospital de la Santa Creu i Sant Pau

6 months ago
Alzheimer

The Sant Pau Research Institute (IR Sant Pau) has led a multicenter project that redefines what is considered normal cognitive performance. The work has resulted in two complementary scientific articl...

A new study shows targeted immunotherapy halves metastasis risk in high-risk early HER2+ breast cancer

by Fundació Clínic per a la Recerca Biomèdica

6 months ago
trastuzumab deruxtecan (T-DXd), high-risk early HER2+ breast cancer

The international DESTINY-Breast05 trial, published in The New England Journal of Medicine, demonstrates that the antibody-drug conjugate trastuzumab deruxtecan (T-DXd) reduces by half the risk of inv...

The antibiotic delafloxacin emerges as a potential therapeutic alternative against Legionella

by Hospital Universitari Germans Trias i Pujol

6 months ago
Legionnaires' disease, Legionella, delafloxacin

A study led by researchers at the Germans Trias i Pujol Research Institute (IGTP) shows, in an experimental laboratory model, that delafloxacin inhibits the intracellular replication of Legionella mor...

Estudian la relación entre el intestino y el hígado y su posible papel clave en la progresión de enfermedades hepáticas

by Universidad de Málaga

Este trabajo sugiere que algunos mecanismos inmunológicos y de disfunción intestinal podrían ser compartidos entre diferentes tipos de daño hepático, como el inducido por fármacos, la hepatitis ...

Lecanemab, donanemab y los inicios de una nueva era en el tratamiento del Alzheimer

by Fundación Pasqual Maragall

6 months ago
Lecanemab, donanemab, Alzheimer

En este artículo echamos un vistazo a las novedades sobre el fármaco lecanemab, el primero aprobado por la vía tradicional por algunas agencias reguladoras del medicamento tras décadas de la últi...

Results from IMMUNOMICS-VHIO platform’s first study demonstrate the efficacy of ultrasensitive liquid biopsy in predicting and monitoring immunotherapy response

by VHIO

6 months ago
immunotherapy, ultrasensitive liquid biopsy, circulating tumor DNA (ctDNA), IMMUNOMICS-VHIO

Published today in Clinical Cancer Research, results from this project’s first study show that ultrasensitive circulating tumor DNA analysis can predict immunotherapy response in patients with advan...