Latest biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

A study shows how international travel affects the gut microbiota

by Instituto de Investigación e Innovación Parc Taulí

2 years ago
gut microbiota

A diverse and resilient microbiota is key to good health, and understanding how travel affects it could help design better preventative strategies

Approved by EMA, novel oral AKT inhibitor in combination improves clinical outcomes and prolongs quality of life in patients with advanced HR+/HER2- breast cancer

by VHIO

2 years ago
capivasertib, fulvestrant, advanced HR+/HER2- breast cancer, AKT inhibitor

The European Medicines Agency (EMA) recently approved the combination of novel AKT inhibitor capivasertib with fulvestrant for patients with hormone receptor (HR)-positive, HER2-negative advanced or m...

The Epicardial Fat of Patients with Type 2 Diabetes Exerts Negative Effects on Cardiac Cells That Are Reversed in the Presence of ApoJ

by Hospital de la Santa Creu i Sant Pau

2 years ago
type 2 diabetes mellitus (T2DM), epicardial fat, apoJ, cardiomyocytes

The cultured epicardial fat from T2DM patients secretes more atherogenic ceramide species and, in the case of T2DM with coronary disease, more saturated free fatty acids than that of non-diabetic pati...

Por qué el ejercicio físico estimula el deseo de mantenerse activo: revelan la relación molecular entre el músculo y el cerebro

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

2 years ago
p38α, p38γ, proteína interleuquina 15 (IL-15), ejercicio

Los músculos activan la p38γ a causa del ejercicio y secretan una cantidad mayor de la proteína interleuquina 15 (IL-15), que tiene un efecto directo sobre la parte de la corteza cerebral que contr...

Investigadores de Bellvitge evalúan el uso de la PCR cuantitativa múltiple en neumonía para reducir el uso de antibióticos

by Hospital Universitari de Bellvitge

2 years ago
neumonía, PCR múltiple

Según el estudio publicado en Nature Communications, la utilización de la PCR cuantitativa múltiple aumentó los diagnósticos etiológicos y redujo el tiempo necesario para conseguirlos.

Identifican dos compuestos que orientan nuevos tratamientos para un tipo de leucemia

by CIMA - Centro de Investigación Médica Aplicada

2 years ago
leucemia mieloide aguda, CM-444 y CM-1758

Investigadores del Cima y de la Clínica Universidad de Navarra demuestran que dos potentes inhibidores, CM-444 y CM-1758, tienen capacidad para promover la diferenciación mieloide en todos los subti...

'Detective’ Algorithm Predicts Best Drugs for Genetic Disorders and Cancer

by IRB Barcelona - Instituto de Investigación Biomédica

2 years ago
RTDetective

RTDetective is a new computational model which can predict which drugs will be most effective in treating diseases caused by premature stop codons, or ‘stop signs’ that appear in DNA and result in...

What we eat does change our cancer risk. CNIO researchers want to know why

by CNIO - Centro Nacional de Investigaciones Oncológicas

2 years ago
cancer, diet

Regarding cancer prevention and food, the recommendation is to avoid obesity and alcohol, as well as eating plenty of vegetables and reducing red meat and processed food. However, on a molecular scale...

Validation of the efficacy of a treatment for migraine in real clinical practice

by Fundació Clínic per a la Recerca Biomèdica

2 years ago
migraine, galcanezumab, calcitonin gene-related peptide (CGRP)

Researchers at the Clínic-IDIBAPS coordinated a study that highlights the efficacy of migraine treatment with a monoclonal antibody, galcanezumab, in routine clinical practice.

HIF-2α inhibitor improves outcomes in patients with previously treated advanced clear cell renal carcinoma

by VHIO

2 years ago
hypoxia-inducible factor 2α (HIF-2α), belzutifan, everolimus

Results of the phase III LITESPARK-005 clinical trial show that treatment with belzutifan versus everolimus significantly improves progression-free survival in patients with advanced clear cell renal ...

Viral defence protein speeds up female stem cell production

by Centre for Genomic Regulation

2 years ago
pluripotent stem cells (iPSCs), interferon gamma (IFNγ), X chromosome, Klinefelter Syndrome

Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice. This discovery that has the potent...

Un antioxidante celular favorece el crecimiento de los tumores linfáticos y su resistencia terapéutica

by CSIC - Centro Superior de Investigaciones Científicas

2 years ago
glutatión, Células Iniciadoras de Tumores (CITs), gen GCLC

Un estudio liderado por el CSIC identifica que el glutatión, uno de los antioxidantes más abundantes en las células, favorece la supervivencia de las células iniciadoras de los tumores linfáticos...