La metformina ejerce parte de sus efectos antidiabéticos a través de un nuevo eje regulador que implica al receptor PPARβ/δ

by CIBERDEM - Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas

Han identificado un nuevo mecanismo molecular que contribuye a explicar los efectos beneficiosos de la metformina, el fármaco más prescrito para el tratamiento de la diabetes mellitus tipo 2.

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Una investigación de la UCLM revela que un receptor clave del cerebro también regula desde dentro la energía celular

by Universidad de Castilla-La Mancha

Investigadores de la Universidad de Castilla-La Mancha del Grupo de Neuroquímica de Ciudad Real han demostrado por primera vez que los receptores de adenosina, unas proteínas clásicamente situadas ...

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Biorce closes a $52.5 million funding round to accelerate the development of its artificial intelligence software for clinical trials

by Biorce

Biorce has closed a $52.5 million investment round (approximately €44.3 million) with the aim of accelerating the development of its artificial intelligence software for clinical trials and strength...

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Orikine Bio receives €2.7M in investment from CDTI Innovación together with two other investors

by Parc Científic de Barcelona

The biotechnology company Orikine Bio, recently established at the Barcelona Science Park, has received an investment of €2.7 million from the SICC Innvierte of CDTI Innovación together with the fu...

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Abdominal fat is associated with early vascular aging in type 1 diabetes

by Instituto de Investigación e Innovación Parc Taulí

A collaborative study by CIBERDEM-ISCIII shows that abdominal fat accelerates vascular aging and increases the risk of long-term vascular complications, even before obesity appears

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Immunotherapy could prevent the loss of neurons in Parkinson's disease

by Universitat Autònoma de Barcelona (UAB)

By analyzing tissue from patients with Parkinson’s disease, and animal and cellular models of the disease, a research team from the Institut de Neurociències of the UAB has shown that the main immu...

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Lleida is promoting a new predictive model to identify complications in the first two days after a mild or moderate traumatic brain injury

by IRB Lleida. Institut de Recerca Biomèdica

The team led by researchers from IRBLleida, the UOC, the UdL, and HUAV would make it possible to reduce unnecessary tests and optimize the use of hospital resources.

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Una nueva terapia celular ofrece resultados prometedores en mujeres con síndrome de Asherman

by INCLIVA

Las células utilizadas en la terapia corresponden a una subpoblación CD133+ derivada de médula ósea, previamente caracterizada por su capacidad regenerativa en el tejido endometrial, lo que refuer...

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Epigenetics Influences the Response to Venetoclax in Acute Myeloid Leukemia

by Hospital de la Santa Creu i Sant Pau

The integrated data analysis identified a small set of genes whose epigenetic regulation showed a particularly consistent association with sensitivity to venetoclax. Among them, EIF5A2 stood out, as h...

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Vall d’Hebron performs the world’s first face transplant from a donor who had requested assisted dying

by Vall d’Hebron

Around 100 professionals were involved in the partial face transplant, an extremely complex surgery considered a composite tissue transplant, using microsurgical vascular and nerve techniques, which c...

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Un estudio del IIS La Fe identifica una nueva vía de protección neuronal frente a la enfermedad de Huntington

by Instituto de Investigación Sanitaria La Fe

El estudio ha identificado fármacos ya disponibles y compuestos naturales capaces de imitar el mecanismo protector y mejorar la función neuronal en modelos de la enfermedad

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Una nueva calculadora de la función de los riñones ayuda a identificar el riesgo de enfermedad renal crónica

by Fundación Jiménez Díaz

Se trata de un programa de screening oportunista dirigido a población general para realizar la determinación de la albuminuria a partir de una muestra de orina, lo que permite detectar precozmente l...

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