Preclinical Research in Drug Development: From Toxicology to Translational Insights

by AMSbiopharma

Through a series of well-established scientific assessments, ranging from toxicology assessments to pharmacokinetics and efficacy models, preclinical research generates essential data to support Inves...

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ORYZON receives European Medicines Agency approval to initiate a Phase Ib study of iadademstat in sickle cell disease

by Oryzon Genomics

Oryzon Genomics, a clinical-stage biopharmaceutical company and a European leader in epigenetics, today announced that the European Medicines Agency (EMA) has approved its Clinical Trial Application (...

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New research points to protecting blood during radiation therapy

by Universidad de Navarra

University of Navarra scientists develop a pioneering model to measure radiation exposure in blood, paving the way for safer and more precise cancer treatments

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Las células estrelladas también son esenciales para el buen funcionamiento del hígado

by CIMA - Centro de Investigación Médica Aplicada

El Dr. Josepmaria Argemí, hepatólogo de la Clínica Universidad de Navarra e investigador del Cima, ha participado en una publicación internacional en la revista Nature que ha demostrado que su pap...

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Descubren un mecanismo celular que altera la microbiota intestinal y que aumenta la aparición de enfermedades múltiples

by CSIC - Centro Superior de Investigaciones Científicas

El estudio, liderado por el CSIC, demuestra que el deterioro asociado a la edad de los linfocitos T CD4 debilita la barrera intestinal, y favorece la inflamación crónica y la senescencia celular

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Un estudio pionero de la UCLM muestra que la combinación de cocaína y alcohol produce un daño cerebral mayor que su consumo por separado

by Universidad de Castilla-La Mancha

Un estudio liderado por la Universidad de Castilla-La Mancha (UCLM) ha demostrado que su combinación no solo potencia los efectos individuales de ambas sustancias, sino que “altera profundamente”...

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Even in People Without Risk Factors, Elevated Lp(a) Increases the Risk of Coronary Heart Disease

by Hospital de la Santa Creu i Sant Pau

This study indicates that people with elevated Lp(a) levels are at increased risk of coronary heart disease even if they don’t have high blood pressure, diabetes, high cholesterol, or a history of s...

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Lipid changes during ageing follow a non-linear pattern and are influenced by gender

by IRB Lleida. Institut de Recerca Biomèdica

Researchers from the University of Lleida and IRBLleida publish one of the most comprehensive lipidomic analyses to date on human ageing

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New, safe, and effective treatment for giant cell arteritis, a disease with few therapeutic options

by Fundació Clínic per a la Recerca Biomèdica

It has been presented Upadacitinib as a new effective and safe therapeutic option for giant cell arteritis, an inflammatory disease that mainly affects the elderly and that until now had few treatment...

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Progress Toward a Population Screening Test for COPD

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

70% of Chronic Obstructive Pulmonary Disease (COPD) cases go undiagnosed. Now, a study led by Hospital del Mar and the Hospital del Mar Research Institute has validated ten metabolites that are altere...

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Melanoma ‘sat-nav’ discovery could help curb metastasis

by Centre for Genomic Regulation

Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body. The malignant cells become dependent on this protein to migrate, pointing...

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Smart pathology slide scanner for diagnosis and patient-specific treatment recommendation in oncology

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

CancerScan aims to develop a smart pathology slide scanner capable of generating patient-specific tumour digital twins to simulate and evaluate treatment outcomes, empowering clinicians to make more a...

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