Latest Cellular and molecular biology biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

Vall d'Hebron tests a new treatment that allows kidney transplantation in inoperable patients until now

by Vall d’Hebron

2 years ago
HLA antigen, imlifidasa, renal disease

The Kidney Transplantation Unit of Vall d'Hebron is the first European transplant center to treat a patient in a Phase III clinical study to demonstrate the efficacy of a new drug that will allow kidn...

A genomic region that is exclusively dedicated to the formation and regeneration of a single organ

by IRB Barcelona - Instituto de Investigación Biomédica

2 years ago
wingless gene, wnt gene, CRISPR/Cas9

Scientists at IRB Barcelona, led by Dr. Marco Milan, have discovered a highly robust mechanism that is used by insects in the development and regeneration of their wings. The researchers have also es...

Researchers show how mutations in ‘dark genome’ cause pancreatic malformations

by Centre for Genomic Regulation

2 years ago
EnhP, CRISPR, gene PTF1A

Researchers at the Centre for Genomic Regulation (CRG) have identified a DNA sequence that is crucial for pancreatic differentiation and function – and for the first time – describe how it works.

Identifican un mecanismo que mantiene la función mitocondrial en las células madre musculares y que puede estimularse en la vejez

by UPF - Universitat Pompeu Fabra

2 years ago
regulador de fisión mitocondrial DRP1, OXPHOS

Un equipo de investigadores liderado por Pura Muñoz-Cánoves, investigadora ICREA del Departamento de Medicina y Ciencias de la Vida de la UPF, ha identificado un mecanismo fisiológico que sustenta ...

Descubren cómo prevenir el dolor neuropático asociado a la quimioterapia en el cáncer de colon

by CSIC - Centro Superior de Investigaciones Científicas

2 years ago
dolor neuropático, cáncer colorrectal, receptor sigma 1, canal iónico TRPA1

Un porcentaje elevado de pacientes oncológicos desarrolla hipersensibilidad al frío y al tacto en las extremidades y la boca a consecuencia de la quimioterapia

Un modelo matemático predice la respuesta de las plantas ante el cambio climático

by CSIC - Centro Superior de Investigaciones Científicas

2 years ago
proteína COP1, termomorfogénesis

Investigadores del CSIC han identificado que una proteína es clave en el desarrollo vegetal en respuesta a temperaturas ambientales elevadas

Evolutionary analysis of the RNA processing landscapes in the primate lineage

by UPF - Universitat Pompeu Fabra

2 years ago
RNA processing landscapes

The study, published in Genome Research, has tackled the analysis of the evolution of RNA diversity in humans and our closely related species. The authors have produced the largest isoform catalog in ...

Self-tolerance in antibody production

by Abyntek

2 years ago
cellular homeostasis, T cells, B cells

Immune tolerance is defined as the tolerance that the immune system presents against molecules of the organism itself, being capable of recognizing these molecules as its own and not developing a resp...

Root growth of crops is altered by climate change

by Centro de Biotecnología y Genómica de Plantas CBGP

2 years ago
Abiotic stresses, ROS, cytokinins, brassinosteroids, auxins and gibberellins

Climate change have a harsh impact on agricultural production, threating food security. Plants perceive, integrate and respond to stress signals differently according to the nature of the combined ...

Flow Cytometry in oncology research

by Abyntek

2 years ago
cytometry, Flow cytometry, inmunofenipado, apoptosis

Flow cytometry is a powerful tool with applications in multiple fields such as cancer biology or immunology. It is a world-widely technology used for the study of the immune system´s response to canc...

Vall d'Hebron trata al primer paciente con terapia celular propia basada en células TIL, un tratamiento experimental contra el cáncer

by VHIO

2 years ago
células TIL

Los Tumour-infiltrating Lymphocytes (TIL) son linfocitos ‒células inmunitarias‒ que se encuentran de forma natural en el tumor. Algunos de estos son capaces de reconocer y eliminar las células t...

Demuestran los beneficios de la metformina como terapia potencial para combatir la enfermedad de Huntington en modelos preclínicos

by CIBERER - Centro de Investigación Biomédica en Red de Enfermedades Raras

2 years ago
enzima proteína quinasa activada por AMP (AMPK), metformina, enfermedad de Huntington (EH), gen HTT

Investigadores de la U755 CIBERER en el Instituto de Investigación Sanitaria La Fe (IIS La Fe) de Valencia han descubierto que activar la enzima proteína quinasa activada por AMP (AMPK), mediante f�...