Latest Cellular and molecular biology biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

Oral health, key to establishing new methods for diagnosing and preventing neurodegenerative diseases such as Alzheimer's

by IRB Lleida. Institut de Recerca Biomèdica

7 months ago
extracellular vesicles (EVs), oral microbiome

Proteins of bacterial origin from the oral microbiome have been identified for the first time within extracellular vesicles present in the human brain

Rejuvenating the blood: a new pharmacological intervention targeting RhoA in blood stem cells

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

7 months ago
haematopoietic system, Rhosin, immunosenescence, RhoA, blood stem cells

According to the results published in Nature Aging, treating blood stem cells ex vivo with the molecule Rhosin leads to their rejuvenation and helps produce healthier blood cells.

The Combination of Carvedilol and Simvastatin Improves Portal Hypertension Control and Inflammatory Markers in Patients with Cirrhosis

by Hospital de la Santa Creu i Sant Pau

7 months ago
carvedilol and simvastatin, portal hypertension, hepatic cirrhosis, hepatic venous pressure gradient (HVPG)

Researchers from the Sant Pau Research Institute (IR Sant Pau) have conducted a clinical trial demonstrating that the combination of two widely available drugs, carvedilol and simvastatin, significant...

Revelan por primera vez un mecanismo esencial para el inicio de la vida en los vertebrados

by CSIC - Centro Superior de Investigaciones Científicas

7 months ago
transición materno-cigótica, genoma cigótico, embriogénesis, CRISPR-RfxCas13d, quinasa Bckdk, proteína Bckdk, acetilaciones

Gracias a una herramienta CRISPR que elimina el ARN, investigadores del CABD han descubierto un nuevo factor con un papel crucial en la fertilidad

A Vall d’Hebron study describes the diversity of cells in which HIV remains latent

by Vall d’Hebron

7 months ago
human immunodeficiency virus (HIV), HIV reservoirs

According to the results, the team highlights the need to use combinations of drugs to reactivate all HIV reservoirs and eliminate the virus from the different tissues where it remains silent.

Investigadores del CIC descubren un mecanismo clave que impulsa la metástasis en el cáncer

by Professional Newco

7 months ago
progresión metastásica del cáncer, ZC3H13, MYB, m6A

El estudio aporta evidencias sobre cómo la pérdida de ZC3H13 favorece la capacidad de las células tumorales para metastatizar, lo que agrava el avance de la enfermedad.

Un nuevo atlas celular revela el proceso de maduración de las células B humanas y su implicación en un tipo de leucemia

by CIMA - Centro de Investigación Médica Aplicada

7 months ago
leucemia linfoblástica aguda tipo B

Investigadores del Cima Universidad de Navarra definen un método de análisis multi-ómico que podría mejorar el diagnóstico y tratamiento de patologías como la leucemia linfoblástica aguda tipo ...

A new strategy developed at Vall d’Hebron will support the diagnosis and monitoring of glioblastoma

by Vall d’Hebron

7 months ago
glioblastoma, ImmunoPET, LIF

ImmunoPET enables in vivo detection of LIF expression, a molecule linked to tumour growth, immune evasion and treatment resistance.

New mutation hotspot discovered in human genome

by Centre for Genomic Regulation

7 months ago
mutation, genome

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we s...

Un análisis de sangre podría permitir la detección ultra-temprana del alzhéimer

by Universidad de Málaga

7 months ago
análisis de sangre, alzhéimer

Encuentran una forma de observar el estado del cerebro a través de la sangre. Este biomarcador podría ser clave para actuar en las fases iniciales de la enfermedad, cuando aún hay margen para inter...

From Inhibition to Destruction – Kinase Drugs Found to Trigger Protein Degradation

by IRB Barcelona - Instituto de Investigación Biomédica

7 months ago
kinase inhibitors, Targeted Protein Degradation (TPD), LYN, BLK, RIPK2

A study led by CeMM-AITHYRA in Viena, with the contribution of IRB Barcelona, reveals that kinase inhibitors not only block enzymatic activity but can also accelerate the degradation of their target p...

The hidden key in the genetic architecture of plants that enables an ultra-fast reaction to cold

by CRAG

7 months ago
Convergent Antisense Transcription (CASt)

Researchers have identified a new genetic mechanism that allows plants to keep acclimation genes ready for a rapid response to stress, which could enhance plant resilience under adverse climatic condi...