3PBIOVIAN Unveils Two Groundbreaking Technology Platforms for AAV and pDNA Manufacturing

by 3PBIOVIAN

AAVion®, a fully integrated AAV manufacturing platform designed to accelerate gene therapy development. A ready-to-use Plasmid Platform intended to meet the increasing demand for plasmid DNA

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DiffInvex reveals how cancers rewire driver genes to beat chemotherapy

by IRB Barcelona - Instituto de Investigación Biomédica

IRB Barcelona researchers have developed a new computational tool that tracks the evolutionary shifts in selection pressure during tumorigenesis and chemotherapy.

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New tool to enhance the effects of immunotherapy in treating cancer

by Fundació Clínic per a la Recerca Biomèdica

Now, a study published in Nature Immunology proposes a new approach to strengthen NK cells in their fight against tumour cells. To do so, researchers used a genetic editing tool called CRISPR-Cas9 to ...

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Mouse memory hinges on a nine-letter protein fragment found only in neurons

by Centre for Genomic Regulation

Researchers at the Centre for Genomic Regulation (CRG) have discovered that one such fragment, a “microexon” just nine amino acids long, is inserted into the DAAM1 protein exclusively in neu...

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La Unidad de Fibrosis Quística de Vall d’Hebron incluye el primer paciente en un ensayo clínico con terapia correctora del ADN

by Vall d’Hebron

Con este tratamiento, tienen como objetivo introducir en el núcleo de la célula una copia funcional del gen CFTR para restaurar su actividad y así reducir el impacto de esta enfermedad

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Unos receptores del gusto amargo en el intestino podrían desempeñar un papel clave en el envejecimiento

by Universitat Rovira i Virgili

La URV lidera un estudio que identifica a dos de estos receptores asociados con cambios metabólicos debidos a la edad, que pueden tener relación con el desarrollo de estrategias enfocadas a un envej...

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Una inmunoterapia experimental logra revertir el daño energético del corazón causado por el colesterol

by Professional Newco

Un mecanismo que hasta ahora no se conocía: el colesterol que transportan las lipoproteínas no solo afecta a los vasos o se deposita en placas, sino que llega a penetrar en las mitocondrias del cora...

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Researchers develop a potential new drug for Alzheimer’s and pain treatment

by Universitat de Barcelona

Researchers of the University of Barcelona led a multidisciplinary team that designed, synthetized and pharmacologically validated these molecules that modulate a therapeutic target which has been lit...

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Marfan Syndrome Increases Risk of Brain Alterations

by Universitat Autònoma de Barcelona (UAB)

A study by the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) reveals that inflammation associated with Marfan syndrome increases vulnerability to neurological diseases...

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Nuevas terapias génicas para la distrofia muscular de Duchenne

by IQS Institut Químic de Sarrià

La Dra. Marta Guerra del grupo GEMAT lidera un proyecto innovador para desarrollar nuevos vectores virales recombinantes híbridos (rAAVs) y seleccionar los que ofrecen la mejor protección inmunitari...

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Sugar-coated nanotherapy dramatically improves neuron survival in Neurodegenerative model

by IBEC - Institut de Bioenginyeria de Catalunya

The new therapy, made of nanofibers and trehalose, a sugar that naturally occurs in plants, traps and neutralizes toxic proteins to stop disease progression. Now trapped, the toxic proteins can no lon...

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25 Genes linked to OCD discovered in largest genetic study ever on the disorder

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

The high-impact scientific journal Nature Genetics has published on Tuesday the study with the largest sample of patients affected by obsessive-compulsive disorder (OCD) ever analyzed, which has made ...

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