Latest Cellular and molecular biology biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

El mapa tridimensional del cáncer revela claves sobre la evolución y resistencia de los tumores

by Revista Genética Médica

2 years ago
HTAN

Nuevos mapas tridimensionales del cáncer permiten comprender mejor su crecimiento en el tiempo y en el espacio.

Viscosity of materials key to cell differentiation

by IBEC - Institut de Bioenginyeria de Catalunya

2 years ago
mesenchymal stem cells (MSCs), integrins, cadherins

An IBEC-led study has revealed how mesenchymal stem cells respond to the viscosity of their environment, a key aspect in their differentiation process.

Researchers molecularly characterise a little-studied group of lymphomas in children and young adults

by Fundació Clínic per a la Recerca Biomèdica

2 years ago
non-Hodgkin B-cell lymphomas, MYC gene, Burkitt lymphoma, large B-cell lymphoma (DLBCL)

This group of non-Hodgkin B-cell lymphomas has characteristics that fall between two of the most common and aggressive lymphomas affecting paediatric patients. An IDIBAPS-Hospital Clínic Barcelona te...

A new CNIC study describes a mechanism whereby cells respond to mechanical signals from their surroundings

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

2 years ago
extracellular matrix (ECM), cellular homeostasis

A study by CNIC, published in Science Advances, offers a new approach to understanding how cells respond to mechanical signals from their environment, redefining the comprehension of the relationship ...

Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

2 years ago
P95HER2 protein, HER2 protein, TECH2Me, TECH2Me small bispecific BiTE®, CAR T, HER2-positive (HER2+) tumors, CAR T.

The p95HER2 protein is found expressed in one third of HER2+ tumors, which represent 4% of all tumors. Led by VHIO investigators, CAR T cells targeting p95HER2 have been engineered to secrete the TECH...

CNAG e IrsiCaixa identifican un perfil inmunológico único en pacientes con VIH resistentes a la progresión de la enfermedad

by Parc Científic de Barcelona

2 years ago
CCR5Δ32, VIH, virémicos no progressoress (VNPs).

El equipo ha descubierto que estos pacientes presentan la mutación genética CCR5Δ32, una menor activación del sistema inmunitario, y niveles reducidos de marcadores asociados a las alteraciones de...

A new avenue of research could allow us to fight antibacterial resistance without creating new antibiotics

by UPF - Universitat Pompeu Fabra

2 years ago
magnesium (Mg²⁺), antimicrobial resistance, L22, ATP

Some bacteria develop mutations in their ribosomes that make them resistant to antibiotics, but they hinder their survival when there is not enough magnesium in the environment

Desvelan el papel clave del pH para activar mecanismos de resistencia de las plantas a la falta de nutrientes

by CSIC - Centro Superior de Investigaciones Científicas

2 years ago
pH, potasio (K+), vacuola, citosol, calcio (Ca²⁺), CML18

Un estudio del CSIC muestra que la señalización del pH en plantas activa la respuesta celular ante la falta de potasio asociada a la agricultura intensiva

Científicas del CSIC identifican un mecanismo que predispone al organismo a sufrir enfermedades metabólicas

by CSIC - Centro Superior de Investigaciones Científicas

2 years ago
gen Tet3, fosforilación oxidativa, glicólisis

Un trabajo liderado desde el Instituto de Biomedicina de Valencia (CSIC) describe en ratones que la ausencia de un gen altera el modo en el que las células obtienen energía

Meningitis Has a Much Greater Impact on Child Mortality than Previously Thought

by ISGlobal - Instituto de Salud Global de Barcelona

2 years ago
meningitis, CHAMPS network

New study by the CHAMPS network reveals high rates of antibiotic-resistant bacteria in hospital-associated cases of meningitis in children under five years of age

Can cells ‘learn’ like brains?

by Centre for Genomic Regulation

2 years ago
negative feedback loops, incoherent feedforward loops

Individual cells appear capable of learning, a behaviour once deemed exclusive to animals with brains and complex nervous systems, according to the findings of a new study led by researchers at the Ce...

Las vesículas extracelulares podrían ser la clave para desarrollar terapias más seguras y efectivas en la enfermedad inflamatoria intestinal

by Institut d'Investigació Sanitària Pere Virgili (IISPV)

Investigadores del Instituto de Investigación Sanitària Pere Virgili (IISPV) y del Instituto de Investigación Germans Trias i Pujol (IGTP) han llevado a cabo una revisión sobre el potencial terap�...