A More Harmful Cholesterol Profile Could Help Explain Part of the Cardiovascular Risk in Well-Controlled Type 1 Diabetes

by Hospital de la Santa Creu i Sant Pau

The study shows that these patients have increased levels of small dense low-density lipoproteins (sdLDL), a type of LDL cholesterol made up of smaller particles that accumulate more easily within art...

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CIC bioGUNE identifies HuR protein as a key regulator of liver glucose and a potential therapeutic target for type 2 diabetes and obesity

by CIC bioGUNE

A study led by researchers from CIC bioGUNE and Universidade de Santiago de Compostela identifies a protein (HuR, also known as ELAVL1) as a key player in regulating sugar production in the liver and ...

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Stool Catcher: Hygienic Stool Sample Collection for Microbiome Studies

by Canvax Biotech

In microbiome studies, reliable results begin with reliable sample collection. Before DNA extraction, sequencing, stabilization, or any downstream analysis, participants need to collect stool samples ...

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Molecular hurdles hindering the total recycling of plastic bottles discovered

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

It has been identified the molecular mechanisms that block the enzymatic degradation of polyethylene terephthalate (PET), one of the world’s most widely manufactured plastics, when it is in its crys...

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A new method expands the potential of a family of compounds in medicine and materials science

by Universitat de Barcelona

Teams from the University of Barcelona and the University of Girona, in collaboration with Nanjing University (China), have developed an innovative method for selectively modifying these boron-rich mo...

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A multi-omic study rules out the role of immature cells in resistance to cancer treatment

by Cima Universidad de Navarra

The results of this study by Cima Universidad de Navarra help improve the accuracy of diagnosis and monitoring for patients with multiple myeloma and primary systemic amyloidosis

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Identifican una nueva estrategia que ayuda a reducir la metástasis del melanoma y a mejorar la inmunoterapia en ratones

by Centro Nacional de Biotecnología (CNB)

En modelos preclínicos, la inhibición de una molécula clave en las primeras fases de la metástasis del melanoma, reduce la propagación del tumor a otros órganos

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A study identifies the endocannabinoid system as a potential therapeutic target in severe acute pancreatitis

by Hospital Universitari Germans Trias i Pujol

The study shows that circulating levels of the endocannabinoid 2-AG decrease in patients who later develop severe acute pancreatitis. This pattern was also observed in the experimental model used by t...

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Targeted therapies improve efficacy in early-phase clinical trials driven by molecular patient selection

by VHIO

Researchers at VHIO have published an article in the journal European Journal of Cancer on the evolution of targeted therapies in early-phase clinical trials. The study shows a progressive improvement...

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Purified Omega-3 Treatment Reduces Cardiac Damage After a Heart Attack by Acting Directly on the Heart

by Hospital de la Santa Creu i Sant Pau

A type of omega-3 fatty acid found in oily fish, used as a medication to lower triglycerides, may directly protect the heart after a heart attack. A study led by the Research Institute of Sant Pau (IR...

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Protein’s role in male reproductive ageing identified

by Universitat Autònoma de Barcelona (UAB)

A study by the UAB and the IJC demonstrates that SIRT7 is a key regulator of the quality of male germ cells and that the deficiency of this protein during ageing can lead to a functional decline in sp...

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