Study Reveals How Key Mutation in Blood Cancers Reprograms Cell Metabolism by Altering Mitochondrial Function

by Hospital de la Santa Creu i Sant Pau

The study shows that the KIT D816V mutation—frequently found in hematologic malignancies such as acute myeloid leukemia (AML) and systemic mastocytosis—increases both the number and activity of mi...

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Extracellular vesicles, key in maternal-embryonic communication, open new possibilities for improving assisted reproduction

by CIC bioGUNE

The research identified differences in the proteins of EVs from oviductal fluid, crucial for embryonic development and maternal-embryo interaction.

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The potential of exosomes in regenerative medicine

by Sermes CRO

Regenerative medicine has advanced significantly in recent decades, and one of the most promising discoveries in this field is exosomes. These tiny extracellular vesicles are revolutionizing how we un...

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Gene therapy reverses symptoms of rare neurological disease in animal models

by Universitat Autònoma de Barcelona (UAB)

A recent study led by the UAB demonstrates the potential of gene therapy to restore motor capacity in an ultra-rare disease, Megalencephalic Leukoencephalopathy with Subcortical Cysts (MLC), even when...

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A Targeted Nanotoxin Activates the Immune Response and Slows Colorectal Cancer Growth in Preclinical Models

by Hospital de la Santa Creu i Sant Pau

Researchers from the Sant Pau Research Institute (IR Sant Pau) have demonstrated, in a preclinical study, the effectiveness of a targeted nanotoxin in inhibiting colorectal cancer growth. The study, p...

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Integrated DNA Technologies and Elegen Partner to Revolutionize Long DNA Synthesis Market

by Integrated DNA Technologies

Strategic partnership marks launch of early access program offering rapid, long, clonal gene synthesis and high-complexity genes up to 15 kb

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Investigadores del IMIBIC identifican características moleculares clave del cáncer de mama asociado al embarazo que podrían mejorar su abordaje terapéutico

by Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)

Identifican características clínicas y moleculares específicas del cáncer de mama asociado al embarazo (PABC) que abren la posibilidad de orientar futuras estrategias terapéuticas personalizadas ...

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Descubrimiento sobre el Papel de las Proteínas Sos1 y Sos2 en la Migración Celular y la Degradación de la Matriz Extracelular

by Professional Newco

Los hallazgo revelan que estas proteínas, tradicionalmente asociadas con la proliferación celular, desempeñan también roles cruciales y complejos, tanto en el control de la migración y dinámica ...

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UB researchers develop a new compound with therapeutic potential against Alzheimer’s disease

by Universitat de Barcelona

The new compound is an inhibitor of soluble epoxide hydrolase (sEH), an enzyme involved in the regulation of several physiological processes, including inflammation and pain response. In the context o...

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Thermo Fisher Scientific Launches the Krios 5 Cryo-Transmission Electron Microscope (TEM), Boosting Productivity and Performance With Enhanced Automation

by Thermo Fisher Scientific

The new Krios 5 Cryo-TEM enables breakthroughs in structural and cellular biology to pioneer new treatments and advance drug discovery

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Un estudio revela cómo la acumulación de hierro y la peroxidación lipídica afectan a las miopatías nemalínicas

by Universidad Pablo de Olavide, de Sevilla

Llevado a cabo por un equipo de investigación del Centro Andaluz de Biología del Desarrollo, el estudio abre nuevas posibilidades para comprender mejor la enfermedad y desarrollar terapias que contr...

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Two new gene-editing tools have been created from microorganisms of the bottom of the ocean: Asterix and Obelix’s CRISPR

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

The new tools, DO1 and DO2, colloquially called Asterix and Obelix, are highly efficient, operate at colder temperatures, and appear to be more specific than the canonical system.

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