New perspectives on the role of the Sialyl-Tn (sTn) glycan in cancer immunology

by CIC bioGUNE

A new study, in collaboration with various international institutions, explores the role of glycans in cancer, focusing on the sTn marker, present in several types of tumors. These findings, published...

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Un ensayo clínico multicéntrico ha evaluado la eficacia y seguridad de la perfusión extendida de antibióticos en la neutropenia febril

by ICO - Institut Català d'Oncologia

Un equipo de investigación del ICO, IDIBELL y Hospital de Bellvitge ha realizado un ensayo clínico aleatorizado en pacientes hematológicos con neutropenia febril para valorar la eficacia de la perf...

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Kynexis Announces Positive Topline Results from Phase 1 Study of KYN-5356, a Potential Treatment for Cognitive Impairment Associated with Schizophrenia

by Ysios Capital

KYN-5356, an innovative, first-in-class small molecule inhibitor of KAT-II, a key enzyme in the kynurenine pathway implicated in schizophrenia, was shown to be safe and well-tolerated in the phase 1 s...

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Investigadores del IMIBIC identifican un nuevo mecanismo molecular implicado en el desarrollo de la enfermedad renal aguda

by Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)

Los resultados de este trabajo señalan a la enzima Nox4 como un actor clave en este tipo de daño renal, sugiriendo que el bloqueo de esta proteína podría constituir una estrategia terapéutica pro...

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INCLIVA analiza mediante biopsia líquida las alteraciones moleculares que ocasionan resistencia al tratamiento en cáncer colorrectal metastásico

by INCLIVA

Han impulsado un proyecto para mejorar la comprensión de las alteraciones moleculares que ocasionan la resistencia al tratamiento convencional y la progresión del cáncer colorrectal metastásico an...

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A new therapy paves the way for the treatment of Fabry disease

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

It has been developed a new therapy based on nanotechnology called nanoGLA for the treatment of Fabry disease. The new therapeutic solution has shown remarkable efficacy in preclinical studies

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Commercial tea bags release millions of microplastics when in use

by Universitat Autònoma de Barcelona (UAB)

Food packaging is a major source of micro and nanoplastic (MNPLs) contamination and inhalation and ingestion is the main route of human exposure.

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Advances made in CAR-T immunotherapy to prevent relapse in multiple myeloma

by Fundació Clínic per a la Recerca Biomèdica

A team from Clínic-IDIBAPS has introduced a modification to a CAR-T immunotherapy for multiple myeloma that makes it more durable, according to results obtained in animal and cellular models.

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Dr Ana Caballero from the Haematology Service Presents Data on the Efficacy of the Academic CAR T-cell Therapy HSP-CAR30 at the ASH Congress

by Hospital de la Santa Creu i Sant Pau

It has been presented the phase I/II clinical trial of the HSP-CAR30 treatment for patients with refractory or relapsed Hodgkin lymphoma and CD30+ T-cell lymphoma. This innovative cellular therapy, a ...

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Investigan un posible tratamiento para eliminar el VIH del cerebro

by Revista Genética Médica

Un tratamiento dirigido a los macrófagos podría contribuir a eliminar la infección de VIH latente en el cerebro.

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Technique developed to detect brain metastases in mice using an ultra-thin light probe

by CNIO - Centro Nacional de Investigaciones Oncológicas

The probe reaches deep into the brain without causing appreciable damage, making it minimally invasive. It projects an ultra-thin beam of light.

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Fast-Track Innovation for Plasmid DNA Production

by Sartorius Stedim Spain

The Sartorius team in Slovenia developed a fully automated system for bacterial cell lysis in plasmid DNA production. Read how they are part of the solution in producing new therapies by addressing a ...

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