Study identifies PARG as a new target to enhance chemotherapy in colorectal cancer

by Hospital Universitari Germans Trias i Pujol

Overall, the findings position PARG as a potential new therapeutic target in colorectal cancer and open the door to the development of combined strategies integrating PARG inhibition with standard che...

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Metabolitos oxidados del colesterol, marcadores tempranos de prediabetes

by CIBER - ISCIII

Un nuevo estudio ha identificado un mecanismo temprano asociado a la resistencia a la insulina. El trabajo, publicado en International Journal of Molecular Science demuestra que la ausencia de la enzi...

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CNIC scientists uncover a novel mechanism involved in inflammation resolution

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

A study published in Immunity reveals that type I interferons (IFN‑I) help resolve inflammation by inducing changes in macrophage mitochondria

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Lung cancer uses the lack of nutrients to become stronger

by IDIBELL - Institut d’Investigació Biomèdica de Bellvitge

An IDIBELL-ICO study identifies the LIF protein as responsible for the adaptability of lung cancer: in the absence of nutrients and oxygen, the tumor responds by secreting LIF and becomes more aggress...

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Orikine Bio receives €2.7M in investment from CDTI Innovación together with two other investors

by Parc Científic de Barcelona

The biotechnology company Orikine Bio, recently established at the Barcelona Science Park, has received an investment of €2.7 million from the SICC Innvierte of CDTI Innovación together with the fu...

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Best practices to extract DNA from bacteria: a practical, lab-ready guide

by Canvax Biotech

Getting reproducible, high-quality DNA is the foundation of any molecular biology workflow. Whether the goal is PCR, qPCR, cloning, or sequencing, following best practices to extract DNA from bacteria...

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Una nueva calculadora de la función de los riñones ayuda a identificar el riesgo de enfermedad renal crónica

by Fundación Jiménez Díaz

Se trata de un programa de screening oportunista dirigido a población general para realizar la determinación de la albuminuria a partir de una muestra de orina, lo que permite detectar precozmente l...

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Epigenetics Influences the Response to Venetoclax in Acute Myeloid Leukemia

by Hospital de la Santa Creu i Sant Pau

The integrated data analysis identified a small set of genes whose epigenetic regulation showed a particularly consistent association with sensitivity to venetoclax. Among them, EIF5A2 stood out, as h...

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Immunotherapy could prevent the loss of neurons in Parkinson's disease

by Universitat Autònoma de Barcelona (UAB)

By analyzing tissue from patients with Parkinson’s disease, and animal and cellular models of the disease, a research team from the Institut de Neurociències of the UAB has shown that the main immu...

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Abdominal fat is associated with early vascular aging in type 1 diabetes

by Instituto de Investigación e Innovación Parc Taulí

A collaborative study by CIBERDEM-ISCIII shows that abdominal fat accelerates vascular aging and increases the risk of long-term vascular complications, even before obesity appears

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Detectado un ‘código secreto’ en la sangre que predice con alta precisión el cáncer colorrectal

by Bionand

Científicos andaluces logran una «huella molecular» en glóbulos blancos que ofrece mejoras a ser consideradas en los próximos años

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Una investigación de la UCLM revela que un receptor clave del cerebro también regula desde dentro la energía celular

by Universidad de Castilla-La Mancha

Investigadores de la Universidad de Castilla-La Mancha del Grupo de Neuroquímica de Ciudad Real han demostrado por primera vez que los receptores de adenosina, unas proteínas clásicamente situadas ...

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