Host cell protein detection in biologics: LC-MS/MS strategies for HCP clearance and regulatory compliance

by AMSbiopharma

HCP monitoring in biopharmaceutical manufacturing is classified as a critical quality attribute in regulatory guidance and not merely a characterization exercise.

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Changing CDMO Late in Development: What Biologics Teams Should Know

by 53Biologics

Changing CDMO late in development is not always a warning sign. Sometimes it is the right decision. But it should be managed as a strategic move, not an administrative transfer.

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¿Cuál es el papel del anatomopatólogo en la Oncología del siglo XXI?

by Centro de Estudios Biosanitarios - CEB

El programa cubre en profundidad: las bases moleculares de la carcinogénesis, proto-oncogenes y oncogenes, genes supresores de tumores, técnicas de patología molecular, patología molecular aplicad...

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Fat-associated liver disease plays a key role in the development of liver cancer

by Fundació Clínic per a la Recerca Biomèdica

Researchers from Clínic-IDIBAPS have participated in a study published in Nature Reviews Cancer that reviews how fat-associated liver diseases, known as steatotic liver diseases, contribute to the de...

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Peptide mapping for biopharmaceutical characterization: LC-MS/MS workflows, PTM analysis, and ICH Q6B compliance

by AMSbiopharma

Peptide mapping has become the gold standard analytical approach for addressing this complexity. It converts a protein into a defined set of peptides that can be individually identified, located withi...

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Push the Limits of Super-Resolution Imaging with abberior CAGE 552

by Tebubio

A UV-activatable red fluorescent dye designed for super-resolution microscopy, delivering outstanding brightness, photostability and localisation precision for advanced biological imaging.

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Una ‘llave molecular’ permite pausar la fotosíntesis para que las plantas acumulen sustancias nutritivas

by CSIC - Centro Superior de Investigaciones Científicas

Una molécula descubierta en el Instituto de Biología Molecular y Celular de Plantas (CSIC-UPV) reprograma las fábricas de energía de las plantas para convertirlas en almacenes de vitaminas, proteÃ...

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A study in Drosophila reveals how the immune system adjusts development in response to excess sugar

by IRB Barcelona - Instituto de Investigación Biomédica

The study, conducted on the vinegar fly Drosophila melanogaster, shows that macrophages detect nutritional stress caused by a high-sugar diet and send a signal to the endocrine system to delay develop...

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Dr. Eduard Batlle receives an ERC Advanced Grant to block metastatic colorectal cancer’s ability to evade treatment

by IRB Barcelona - Instituto de Investigación Biomédica

The Plastic_CRC project will explore ways to reduce the adaptive capacity of tumours in order to combat therapeutic resistance and boost treatment efficacy.

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Physical exercise could help modulate the immune response in type 1 diabetes

by Hospital Universitari Germans Trias i Pujol

A review published in Diabetes Care analyses experimental and clinical evidence on the role of physical activity as a potential complementary strategy to promote immune regulation, preserve beta cells...

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Bellvitge identifica una alteración genética que ayuda a prevenir complicaciones de la enfermedad de Rendu-Osler

by Hospital Universitari de Bellvitge

El Hospital Universitario de Bellvitge y el Instituto de Investigación Biomédica de Bellvitge (IDIBELL) han identificado una alteración cromosómica recurrente no descrita previamente en la telangi...

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‘Living medicine’ and AI-designed proteins to fight lung cancer from within

by Centre for Genomic Regulation

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona will develop new methods that combine protein design software and generative AI to engineer safer, more effective drugs.

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