La melatonina protege las células sanas y tumorales del páncreas

by Universidad de Extremadura

Estudios del grupo de investigación de Fisiología Celular de la UEx demuestran que la melatonina induce la muerte de células malignas del páncreas y protege, a su vez, las células sanas

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The protein that keeps cells static is found to play a key role in cell movement

by IRB Barcelona - Instituto de Investigación Biomédica

Researchers at IRB Barcelona reveal that the protein E-Cadherin is required for groups of diverse cells to migrate together. Tumours with intermediary levels of E-Cadherin generally have a poorer prog...

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Una investigación constata el papel clave de una proteína para entender la enfermedad de Parkinson

by Universidad Católica de Valencia

La alteración de LRRK2 podría, a su vez, alterar determinadas rutas de supervivencia celular que sería la causa de la muerte de las células cerebrales, lo que podría allanar el camino para el des...

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Mechanism identified by which some pathogens regulate the expression of antibiotic resistance genes

by Centro Nacional de Biotecnología (CNB)

“Stimulation and inhibition of transcription is the mechanism used by ω2 to control the copy number, efficient distribution and survival of the plasmid” explains Juan Carlos Alonso, one of the au...

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Presence of genetic mutation across several tumor types may help develop more precise anti-cancer therapies

by Vall d’Hebron

The basket trial design of this study maximizes the possibility of simultaneously detecting early signs of activity across multiple tumor types. The detection of these alterations in tumors act as bio...

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Nueva estrategia farmacológica para un tratamiento más rápido y eficaz de la depresión

by Fundació Clínic per a la Recerca Biomèdica

La depresión es la patología psiquiátrica con mayor repercusión socioeconómica y requiere de medicación y psicoterapia para ser tratada. El European Brain Council estima su coste anual en Europa...

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Key protein in cilia assembly identified

by IRB Barcelona - Instituto de Investigación Biomédica

The study, published in Current Biology, focuses on cilia, the cellular structures that by sensing chemicals and mechanical forces allow for smelling, hearing, and many other essential functions.

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Tumour suppressor genes curb growth in neighbouring cells

by IRB Barcelona - Instituto de Investigación Biomédica

Researchers at IRB Barcelona unravel a role for tumour suppressor genes in restricting the growth of neighbouring cell populations. The study, published yesterday in PLoS Biology, might have implicati...

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Ratones y plantas comparten un mecanismo de control en la división celular

by Universidad Complutense de Madrid

Investigadores de la Universidad Complutense de Madrid han estudiado los mecanismos que regulan los intercambios de información genética producidos durante la división celular que origina los gamet...

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Attacking bioenergetic metabolism to improve anti-cancer therapies using taxol

by CNIO - Centro Nacional de Investigaciones Oncológicas

A new study has now proven that blocking glycolysis - the molecular mechanism that makes it possible to extract energy from glucose - is especially damaging to the division of cancer cells and that sp...

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Inntags: new tools for innocuous protein tagging

by IRB Barcelona - Instituto de Investigación Biomédica

A study conducted in collaboration with the CSIC, BSC and UB provides a new approach to follow cellular proteins more closely. The target proteins labelled with inntags do not show detectable alterati...

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A switch for health heart muscle

by Centre for Genomic Regulation

CRG researchers have discovered a protein, called Mel18, that regulates the development of heart muscle. Faults in the production of Mel18 in early cardiac cells may play a role in heart defects

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