Identity & Chemical Purity of Polymeric Excipients

by Curapath

Polymeric excipients are key to advanced drug‑delivery systems, as their structure and impurity profile directly affect safety, stability, and in vivo performance. With rising regulatory expectation...

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KRAS degradation induces rapid lung cancer regression in preclinical mouse models

by IRB Barcelona - Instituto de Investigación Biomédica

It has been demonstrated that eliminating mutated KRAS protein using PROTACs induces rapid tumour regression in mouse models of lung adenocarcinoma

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Un estudio preclínico abre la puerta a tratamientos personalizados de la hipertensión en hombres y mujeres

by INCLIVA

Este estudio muestra que la hipertensión arterial altera el funcionamiento de los vasos sanguíneos renales tanto en machos como en hembras, aunque no lo hace de la misma manera. En ambos casos se ob...

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Hallada una proteína clave para la recuperación del corazón tras un ataque cardíaco

by Instituto de Biomedicina de Sevilla - IBIS

El estudio apunta a Orai1 como un regulador esencial para regenerar nuevos vasos sanguíneos necesarios para reparar el corazón después de un infarto.

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Fat molecule inside cell nucleus shifts with cell division

by Centre for Genomic Regulation

invResearchers have shown that a type of fat molecule, long associated with signalling at the cell's outer membrane, also operates inside the nucleus on a schedule that matches the rhythm of cell divi...

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A new way to observe the release of proteins encapsulated in nanoparticles

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Precision medicine aims to transport therapeutic agents, such as molecules, proteins or RNA, to the exact place where they need to act within the body. One of the most promising strategies is the use ...

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Un estudio liderado por el Hospital público 12 de Octubre asocia el uso de antibióticos de amplio espectro con peores resultados clínicos en pacientes con mieloma múltiple

by Hospital Universitario 12 de Octubre

Han demostrado por primera vez que la administración de antibióticos de amplio espectro, antes de iniciar un tratamiento con anticuerpos biespecíficos —una forma avanzada de inmunoterapia—, se ...

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See Centrioles, Cilia and Flagella in Live Cells Without Genetic Engineering

by Tebubio

CenSpark650: First-in-class dual-ligand fluorescent probe for selective imaging of centrioles and ciliary microtubules

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Researchers develop a blood test that can detect pancreatic cancer within minutes

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

This is the first trial of a diagnostic test that identifies, in blood plasma, a protein (AXL) that acts as a biomarker for pancreatic ductal adenocarcinoma, the most common and deadliest form of panc...

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Immunity against measles: a tool against cancer

by Universitat Politècnica de València

A team led by the UPV proposes harnessing the immunological memory generated by vaccination to help the body recognise and eliminate tumour cells

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Integrated DNA Technologies Announces End-to-End Oncology Research Workflows Optimized on Illumina Software for Faster Insights

by Integrated DNA Technologies

IDT announces a collaboration with Illumina to enable integrated oncology research workflows that combine IDT library preparation with DRAGEN™ secondary analysis, streamlining the path from sequenci...

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Idoneidad de los modelos 3D disponibles para el estudio de la latencia del cáncer

by Biodonostia

El grupo de Bioingeniería en Regeneración y Cáncer ha recopilado la información existente sobre los modelos 3D disponibles para la investigación de la latencia del cáncer.

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