It has been identified 24 neopeptides that could be good targets for designing preventive cancer vaccines in people with Lynch syndrome. The results show that the selected peptides are repeated among ...
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It has been designed a strategy to inhibit the expression of PCSK9, a protein that plays a decisive role in modulating plasma levels of low-density lipoprotein cholesterol (LDL-C). The new method, bas...
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Large-scale study aims to create comprehensive map of the human proteome to monitor changes reflecting human health and disease
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La Dra. Iris Pontón defendió su tesis doctoral en IQS; en la que ha desarrollado nuevos sistemas de liberación controlada de fármacos con nanopartículas mesoporosas de sílice para superar los de...
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This is an analysis on an unprecedented scale. They studied over 140,000 versions of the Aβ42 peptide, which forms harmful plaques in the brain. It is the first map to reveal how mutations affect a p...
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The new study, conducted in animal models, describes a repressor factor that blocks brown fat activity: the ACBP protein. Under normal conditions, this protein would regulate when brown fat activity i...
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Desveladan el mapa cerebral de las proteínas en las fases tempranas de la enfermedad de Alzheimer utilizando una novedosa técnica llamada MALDI imaging. Esta ha permitido mostrar, por primera vez, a...
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Con este estudio se ha constatado que la muestras cerebrales de pacientes de alzhéimer contienen unas isoformas patogénicas del péptido beta-amiloide que favorecen en mayor medida la formación de ...
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El proyecto propone la inhibición de las proteínas ETV4 y ETV5, miembros de la familia PEA3, como complemento a los inhibidores de KRAS. El objetivo es superar la resistencia que limita la eficacia ...
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The work, led by a team from IDIBELL and CSIC, manages to visualise how embryonic cells eliminate bacterial infections before the formation of the immune system.
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Patients with Chronic Obstructive Pulmonary Disease (COPD) who suffer from sarcopenia, meaning a loss of strength and muscle capacity, show higher levels of a protein linked to muscle growth regulatio...
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The goal is to create protein nanoparticles that are useful in earlier cancer detection and to accelerate the development of more effective drugs with fewer side effects
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La mejor actitud que podemos adoptar es la de trat...
The research team observed changes in head circumf...
AtCDF3 gene induced greater production of sugars a...
En nuestro post hablamos sobre este interesante tipo de célula del...
Acute myeloid leukemia (AML) does more than infiltrate the lungs: it a...
