CIC bioGUNE identifies HuR protein as a key regulator of liver glucose and a potential therapeutic target for type 2 diabetes and obesity

by CIC bioGUNE

A study led by researchers from CIC bioGUNE and Universidade de Santiago de Compostela identifies a protein (HuR, also known as ELAVL1) as a key player in regulating sugar production in the liver and ...

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Identifican una nueva estrategia que ayuda a reducir la metástasis del melanoma y a mejorar la inmunoterapia en ratones

by Centro Nacional de Biotecnología (CNB)

En modelos preclínicos, la inhibición de una molécula clave en las primeras fases de la metástasis del melanoma, reduce la propagación del tumor a otros órganos

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Protein’s role in male reproductive ageing identified

by Universitat Autònoma de Barcelona (UAB)

A study by the UAB and the IJC demonstrates that SIRT7 is a key regulator of the quality of male germ cells and that the deficiency of this protein during ageing can lead to a functional decline in sp...

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KRAS degradation induces rapid lung cancer regression in preclinical mouse models

by IRB Barcelona - Instituto de Investigación Biomédica

It has been demonstrated that eliminating mutated KRAS protein using PROTACs induces rapid tumour regression in mouse models of lung adenocarcinoma

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Hallada una proteína clave para la recuperación del corazón tras un ataque cardíaco

by Instituto de Biomedicina de Sevilla - IBIS

El estudio apunta a Orai1 como un regulador esencial para regenerar nuevos vasos sanguíneos necesarios para reparar el corazón después de un infarto.

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Opening the door to new therapeutic strategies in patients with bronchiectasis

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

People diagnosed with bronchiectasis show loss of muscle mass early on and in mild and moderate stages of this respiratory disease. This is why it is so important to understand the molecular mechanism...

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A new way to observe the release of proteins encapsulated in nanoparticles

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

Precision medicine aims to transport therapeutic agents, such as molecules, proteins or RNA, to the exact place where they need to act within the body. One of the most promising strategies is the use ...

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Researchers develop a blood test that can detect pancreatic cancer within minutes

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

This is the first trial of a diagnostic test that identifies, in blood plasma, a protein (AXL) that acts as a biomarker for pancreatic ductal adenocarcinoma, the most common and deadliest form of panc...

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Immunity against measles: a tool against cancer

by Universitat Politècnica de València

A team led by the UPV proposes harnessing the immunological memory generated by vaccination to help the body recognise and eliminate tumour cells

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Científicos de la Universidad de Salamanca descubren un ‘interruptor’ cerebral clave en el autismo y la esquizofrenia

by Universidad de Salamanca

'Molecular Psychiatry' publica el avance internacional que abre vías para el tratamiento de los trastornos del neurodesarrollo e identifica por primera vez a la proteína MSK1 como regulador esencial...

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AI enables the design of new molecules that selectively target specific cells

by IRB Barcelona - Instituto de Investigación Biomédica
  • 28 days ago
  • AI

Researchers at IRB Barcelona develop a computational framework that creates molecules with selective activity in specific cell types, without the need to start from a predefined molecular target.

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Identification of the signals triggering the maturation of pulmonary macrophages

by Centro Nacional de Biotecnología (CNB)

RXR is a protein found inside cells, where it detects the presence of lipids and vitamin A derivatives. Based on these signals, RXR controls the activation of cellular programmes that allow macrophage...

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