Latest Proteins biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

Human eggs power down to protect themselves

by Centre for Genomic Regulation

12 months ago
lysosomes and proteasomes, reactive oxygen species (ROS)

Human eggs are some of the most patient cells in the body, lying dormant for decades until needed. A study published today in The EMBO Journal shows that the cells deliberately slow the activity of th...

Amino acids play a key role in how cells respond to drugs

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

12 months ago
Amino acids, cannabinoid receptor type 2 (CB2), G protein-coupled receptors (GPCRs)

Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like bricks that communicate with each other within a structure. In this way, th...

An aggressive childhood cancer case opens new avenues for advanced cell therapies

by IRB Barcelona - Instituto de Investigación Biomédica

12 months ago
Rhabdoid tumours, T cells, Cellular immunotherapy, TCR-T, immune checkpoint inhibitors (ICI)

After receiving chemotherapy and radiotherapy, the patient also began immunotherapy with immune checkpoint inhibitors (ICI), a treatment that boosts the ability of lymphocytes to recognise and combat ...

La molécula AMPc, una diana terapéutica para recuperar la capacidad locomotora tras una lesión medular

by Universidad Pablo de Olavide, de Sevilla

12 months ago
lesión medular grave, molécula AMPc, herramienta optogenética bPAC

Investigadores de la Universidad Pablo de Olavide colaboran en un estudio pionero liderado por el Centro de Investigación Príncipe Felipe que acelera la recuperación en animales tras una lesión me...

Descubren un mecanismo que controla el sistema de alarma celular durante la replicación del material genético

by CSIC - Centro Superior de Investigaciones Científicas

12 months ago
replicación del ADN, POLA/PRIM (ADN polimerasa alfa/primasa), proteína VCP/p97, ubiquitina

Investigadores del Centro de Biología Molecular Severo Ochoa (CBM, CSIC-UAM) han identificado un mecanismo que permite a las células copiar su ADN de manera segura y ordenada. Esto permite comprende...

More reliable bioinformatics tools for the study of proteins

by Universitat Autònoma de Barcelona (UAB)

12 months ago
liquid-liquid phase separation (LLPS)

IBB researchers have generated a high-quality dataset to help better understand the proteins involved in a key biological process through which they form condensates, and the role they play in functio...

Genes para predecir la respuesta al tratamiento endocrino previo a la cirugía en cáncer de mama luminal

by Biodonostia

11 months ago
cáncer de mama luminal, plataforma de expresión génica PAM50

Este estudio concluye que el análisis de los genes (mediante plataformas génicas como PAM50) en las muestras de las pacientes en quienes se indicó tratamiento endocrino previo a la cirugía puede s...

New Blood Biomarker Identified That Predicts the Severity of Coronary Artery Disease

by Hospital de la Santa Creu i Sant Pau

11 months ago
EPAC1, severe coronary artery disease (CAD), vascular smooth muscle cells (VSMCs), hypoxia, atherosclerosis

Using high-resolution proteomic techniques, the team identified that the protein EPAC1 (Exchange Protein directly Activated by cAMP 1) is secreted in lower amounts by these cells when they are exposed...

Una tesis doctoral desarrolla nanovehículos con una corona proteica artificial para tratar el cáncer de páncreas

by IQS Institut Químic de Sarrià

11 months ago
adenocarcinoma ductal pancreático (PDAC)., nanopartículas mesoporosas de sílice (MSN), albúmina

La investigación de la Dra. Iris Pontón, dirigida por el Dr. David Sánchez García en el grupo GEMAT de IQS, presenta nuevos sistemas basados en nanopartículas de sílice para superar las barreras...

Identifican una nueva estrategia para eliminar el colesterol de las células vasculares y frenar la aterosclerosis

by Professional Newco

Un nuevo estudio identifica una vía terapéutica prometedora para restaurar la capacidad de las lipoproteínas HDL de eliminar el colesterol de las células musculares lisas vasculares (VSMCs), impli...

One billion-year-old rules of protein stability revealed

by Centre for Genomic Regulation

11 months ago
FYN-SH3

The study turns this idea on its head. Researchers at the Centre for Genomic Regulation (CRG) in Barcelona and the Wellcome Sanger Institute in Hinxton, UK, studied a human protein domain (the functio...

New insights into the molecular dialogue between plants and bacteria

by Centro de Biotecnología y Genómica de Plantas CBGP

11 months ago
Rhizobium bacteria, legumes, nitrogen, zinc

A study conducted by researchers from the Associations of Symbiotic Bacteria with Plants Group at CBGP has revealed that two zinc transporter systems contribute to the symbiosis of Rhizobium with pea ...