Latest Proteins biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

New biomarker to determine whether immunotherapy may work in people with colon and rectal cancer

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

3 months ago
CTHRC1(+) CAFs, TGF-beta, immunotherapy, colon and rectal cancer, CTHRC1

The study, led by the Hospital del Mar Research Institute and IRB Barcelona, shows that the determination of this protein, CTHRC1, can be used to assess patient prognosis. At the same time, it opens u...

Microbes show almost universal potential for biodegrading plastics

by Universitat Autònoma de Barcelona (UAB)

Researchers have identified more than 600,000 microbial proteins capable of breaking down natural and synthetic plastics, revealing a far broader biodegradation potential across microbes than previous...

A CNIO group contributes to identifying which breast lesions will progress to cancer, thus helping avoid overtreatment

by CNIO - Centro Nacional de Investigaciones Oncológicas

2 months ago
precancerous breast lesions, RANK protein, luminal cells, infidel cells

20% of breast cancer diagnoses are actually precancerous lesions. As it is not yet possible to know which ones will progress to cancer, the vast majority are treated as if they were already cancerous

The CATHERINE trial begins as the first clinical trial of an innovative CAR-T therapy that triggers a dual anti-tumour response in HER2+ solid tumours

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

2 months ago
CAR-T therapy, HER2, p95HER2, TECH2Me, HER2+ solid tumours

After more than a decade of research, a new-generation CAR-T therapy developed by VHIO, in collaboration with the Hospital del Mar Research Institute, has been administered to patients for the first t...

Nuevo biosensor para detectar tuberculosis activa

by Universitat Politècnica de València

2 months ago
Mycobacterium tuberculosis, tuberculosis, proteína MPT64

Un equipo del IDM lidera el desarrollo de un sensor que abre un nuevo camino para la detección de forma rápida, selectiva y barata de esta infección bacteriana

Recombinant Protein Production Under GMP: Key Decisions That Define Success

by 53Biologics

2 months ago
GMP Manufacturing, Recombinant Protein

When companies evaluate GMP recombinant protein manufacturing, discussions often revolve around timelines, batch size or price per gram.

One root, many responses: how each cell helps plants cope with phosphorus scarcity

by Centro de Biotecnología y Genómica de Plantas CBGP

2 months ago
Phosphorus, SR45

Phosphorus is an essential nutrient for plants, but its scarcity in soils limits agricultural production. Understanding how roots adapt to this shortage is key to advancing more sustainable and effici...

A study expands the genetic basis of an encephalopathy associated with epilepsy and autism

by Universitat de Barcelona

2 months ago
SYNGAP1 gene, SYNGAP1 encephalopathy, p.Ala591Pro, p.Val447Leufs*5, p.Thr674Profs*36 and p.Arg143Glnfs*9, SHANK1, SHANK3 and NLGN2

A multicentre study describes the wide variability in clinical symptoms among patients and reveals that the severity of the disease does not depend exclusively on the SYNGAP1 gene, but on other geneti...

Mutations in the 'translators' of the human cell alter the reading of the genetic code in cancer and ageing

by IRB Barcelona - Instituto de Investigación Biomédica

2 months ago
codons, transfer RNAs (tRNA)

A study by IRB Barcelona reveals that transfer RNA (tRNA) genes accumulate mutations at a frequency up to nine times higher than average

Identificada una respuesta protectora de la pared vascular en el aneurisma de aorta abdominal

by CIBER - ISCIII

2 months ago
aneurisma de aorta abdominal (AAA), matriz extracelular, trombospondina 4 (TSP4), gen THBS4

El estudio identifica un nuevo mecanismo protector implicado en el desarrollo del aneurisma de aorta abdominal (AAA), una enfermedad cardiovascular grave para la que actualmente no existen tratamiento...

A study by the University of Extremadura identifies a key protein for the protection of the respiratory epithelium

by Universidad de Extremadura

2 months ago
caveolin-1 protein, multiciliated cells, secretory cells, Notch signaling pathway

Researchers at the University of Extremadura (UEx) have identified the caveolin-1 protein as a new regulator of the differentiation of respiratory epithelial cells, a key tissue for defense against vi...