Latest Proteins biotechnology articles and news on biotech industry leaders, emerging biotech companies in Spain

A study identifies a key protein in the response to 'one-two' therapies in oncology

by IdiBGi

1 year ago
'one-two' therapies, senescence, senolytics, apoptosis, protein BCL-xL

Researchers from the ProCURE ICO-Girona/IDIBGI program find one of the keys to improving the elimination of senescent tumor cells.

Investigadores del CABD descubren un nuevo mecanismo celular con potencial terapéutico en enfermedades neurodegenerativas

by Universidad Pablo de Olavide, de Sevilla

1 year ago
chaperona EMC, proteína Lam6/Ltc1, ergosterol, ketoconazol, emulsionante tween20 (E432)

Este estudio allana el camino para nuevos enfoques médicos centrados en la modulación de la fluidez de las membranas celulares

IDIVAL Researchers Explore a New Drug Combination for Chronic Lymphocytic Leukaemia

by Instituto de Investigación Marqués de Valdecilla

1 year ago
Chronic lymphocytic leukaemia (CLL), proteostasis, Pevonedistat, Laduviglusib

The study has shown that Pevonedistat, a drug that blocks protein degradation, enhances the effect of Laduviglusib, an inhibitor previously shown to induce the death of leukaemic B lymphocytes. The co...

Ambicioso proyecto nacional para implantar un modelo preclínico de medicina personalizada en la detección precoz de las demencias

by Instituto de Investigación Biomédica de Salamanca - IBSAL

1 year ago
deterioro cognitivo

La investigadora del IBSAL Ángeles Almeida lidera el consorcio MedPer_DC, integrado por 11 grupos de investigación de referencia y financiado con 1,7 millones de euros por el ISCIII, para validar un...

New pathways discovered for drugs to act on cells

by IMIM - Institut Hospital del Mar d'Investigacions Mèdiques

1 year ago
G protein-coupled receptors (GPCRs)

Previously unknown access points in cell membrane proteins have been discovered, enabling laboratory-developed drugs to modify cell function.

Una investigación del CNIO descubre cómo el melanoma y otros tumores logran ocultarse y resistir a la inmunoterapia

by CNIO - Centro Nacional de Investigaciones Oncológicas

1 year ago
Midkine, melanoma, células dendríticas

Las células de melanoma, el cáncer de piel más agresivo, producen una proteína que bloquea el reconocimiento y eliminación del tumor por parte del sistema inmunitario, las defensas naturales del ...

Identificada una nueva estrategia terapéutica para el tratamiento de cáncer biliar

by Biodonostia

1 year ago
sumoilación, colangiocarcinoma (CCA), ML792 y S-adenosilmetionina (SAMe)

Investigadores e investigadoras del Área de Enfermedades Hepáticas y Gastrointestinales del Instituto de Investigación Sanitaria Biogipuzkoa, han coordinado un estudio colaborativo internacional qu...

Extracellular vesicles, key in maternal-embryonic communication, open new possibilities for improving assisted reproduction

by CIC bioGUNE

1 year ago
extracellular vesicles (EVs), differentially abundant proteins (DAPs), MDH1, IDH1, and TPI1

The research identified differences in the proteins of EVs from oviductal fluid, crucial for embryonic development and maternal-embryo interaction.

The potential of exosomes in regenerative medicine

by Sermes CRO

1 year ago
exosomes, regenerative medicine

Regenerative medicine has advanced significantly in recent decades, and one of the most promising discoveries in this field is exosomes. These tiny extracellular vesicles are revolutionizing how we un...

Desarrollan una estrategia innovadora para reducir la resistencia a los antibióticos de una superbacteria

by CSIC - Centro Superior de Investigaciones Científicas

1 year ago
resistentes al antibiótico meticilina (MRSA), BlaR1, Staphylococcus aureus

Un estudio internacional con investigadores del CSIC ha diseñado un compuesto que impide la activación de la resistencia en el patógeno ‘Staphylococcus aureus’

Gene therapy reverses symptoms of rare neurological disease in animal models

by Universitat Autònoma de Barcelona (UAB)

1 year ago
Megalencephalic Leukoencephalopathy with Subcortical Cysts (MLC), gene therapy, MLC1 gene

A recent study led by the UAB demonstrates the potential of gene therapy to restore motor capacity in an ultra-rare disease, Megalencephalic Leukoencephalopathy with Subcortical Cysts (MLC), even when...

A Targeted Nanotoxin Activates the Immune Response and Slows Colorectal Cancer Growth in Preclinical Models

by Hospital de la Santa Creu i Sant Pau

1 year ago
microsatellite stable (MSS), T22-DITOX-H6, CXCR4, pyroptosis

Researchers from the Sant Pau Research Institute (IR Sant Pau) have demonstrated, in a preclinical study, the effectiveness of a targeted nanotoxin in inhibiting colorectal cancer growth. The study, p...