UB researchers identify a key protein in the inflammatory response to infections

by Universitat de Barcelona

A deficiency of Polμ protein could be the cause of certain autoinflammatory diseases, conditions in which the immune system is activated inappropriately, leading to chronic inflammation and tissue da...

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Nueva vía para mejorar la inmunoterapia en cáncer de hígado

by Cima Universidad de Navarra

Científicos del Cima Universidad de Navarra confirman que la inhibición de la proteína G9a con nuevos fármacos experimentales mejora la eficacia del tratamiento en modelos animales

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mRNA–LNP Bispecific Antibodies: Demonstrating T-Cell Activation and Targeted Tumor Killing

by Tebubio

La tecnología de ARNm-LNP ofrece un enfoque alternativo al permitir la expresión transitoria de anticuerpos biespecíficos tras la administración de ARNm-LNP. Esto facilita ciclos de diseño y prue...

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Una molécula protege el páncreas de la toxicidad asociada a la diabetes tipo 2

by CSIC - Centro Superior de Investigaciones Científicas

En fase preclínica, actúa como un “escudo molecular” impidiendo la formación de agregados de la proteína amilina, que destruyen las células productoras de insulina

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Researchers discover a molecular switch that guides the movement of neurons during brain development

by Universitat de Barcelona

During brain development, neurons can regulate their movement until they reach their final destination thanks to a “molecular switch” involving the protein Teneurin 4 (Ten4). This protein can guid...

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Un estudio identifica un mecanismo clave en la degeneración de las neuronas motoras en la ELA

by CSIC - Centro Superior de Investigaciones Científicas

Los resultados conseguidos por el Instituto de Neurociencias (CSIC-UMH) apuntan a un sistema celular de ‘limpieza selectiva’ como posible diana terapéutica para frenar esta enfermedad

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A study co-led by IDIBGI identifies the origin of sleep disorders in FOXP1 syndrome

by IdiBGi

The results indicate that genes of the FOXP family are essential during the development of the nervous system to ensure a normal sleep pattern in adulthood.

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New key role of a protein in brain development discovered

by IRB Lleida. Institut de Recerca Biomèdica

These findings open up new avenues for a better understanding of how the brain develops and what may go wrong in developmental neurological disorders

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Un estudio preclínico sugiere que la vitamina C podría reducir la resistencia del cáncer colorrectal a la quimioterapia

by Fundación Jiménez Díaz

Los investigadores han comprobado que el metabolismo celular, además de soporte energético para las células tumorales, es un regulador que activa la expulsión de los fármacos, disminuyendo su efi...

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CBGP scientists identify a regulator that adjusts crop flowering to heat

by Centro de Biotecnología y Genómica de Plantas CBGP

The identification of the chromatin reader MBD4 expands our understanding of how flowering responses are regulated under warm ambient temperatures.

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A new experimental strategy enables the elimination of proteins involved in pathological processes

by Institute for Advanced Chemistry of Catalonia (IQAC-CSIC)

It has been developed a strategy that enables the forced elimination of proteins that help tumors survive chemotherapy. This finding opens a new avenue to tackle resistance to cancer treatments, one o...

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