A deficiency of Polμ protein could be the cause of certain autoinflammatory diseases, conditions in which the immune system is activated inappropriately, leading to chronic inflammation and tissue da...
Read moreCientíficos del Cima Universidad de Navarra confirman que la inhibición de la proteína G9a con nuevos fármacos experimentales mejora la eficacia del tratamiento en modelos animales
Read moreLa tecnología de ARNm-LNP ofrece un enfoque alternativo al permitir la expresión transitoria de anticuerpos biespecíficos tras la administración de ARNm-LNP. Esto facilita ciclos de diseño y prue...
Read moreEn fase preclínica, actúa como un “escudo molecular” impidiendo la formación de agregados de la proteína amilina, que destruyen las células productoras de insulina
Read moreDuring brain development, neurons can regulate their movement until they reach their final destination thanks to a “molecular switch” involving the protein Teneurin 4 (Ten4). This protein can guid...
Read moreThe finding explains how the absence of a key protein in the structure of bile ducts promotes the onset of fibrosis.
Read moreLos resultados conseguidos por el Instituto de Neurociencias (CSIC-UMH) apuntan a un sistema celular de ‘limpieza selectiva’ como posible diana terapéutica para frenar esta enfermedad
Read moreThe results indicate that genes of the FOXP family are essential during the development of the nervous system to ensure a normal sleep pattern in adulthood.
Read moreThese findings open up new avenues for a better understanding of how the brain develops and what may go wrong in developmental neurological disorders
Read moreLos investigadores han comprobado que el metabolismo celular, además de soporte energético para las células tumorales, es un regulador que activa la expulsión de los fármacos, disminuyendo su efi...
Read moreThe identification of the chromatin reader MBD4 expands our understanding of how flowering responses are regulated under warm ambient temperatures.
Read moreIt has been developed a strategy that enables the forced elimination of proteins that help tumors survive chemotherapy. This finding opens a new avenue to tackle resistance to cancer treatments, one o...
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