Cuál es el papel del factor de crecimiento transformante beta?

by Labo'Life

El Factor de Crecimiento Transformante β (TGF-β) es una proteína que pertenece a la superfamilia de los factores de crecimiento y que presenta multitud de funciones. Entre ellas, destaca su papel e...

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Two proteins safeguard skin stem cells

by IRB Barcelona - Instituto de Investigación Biomédica

The proteins identified, Dnmt3a y Dnmt3b, are crucial for the self-renewal of skin stem cells as they trigger the first step of the genetic programme of these cells. “Without them, this programme is...

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A new animal model to study the potential of CD6 receptor as a therapeutic target for immune-mediated diseases

by IDIBAPS - Institut d'Investigacions Biomèdiques August Pi i Sunyer

IDIBAPS researchers have developed, for the first time, an animal model to study the role of the CD6 protein, a T lymphocyte molecule involved in the susceptibility for developing autoimmune diseases....

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Discovered a mechanism that allows cancer to survive without glucose

by CNIO - Centro Nacional de Investigaciones Oncológicas

The finding provides important clues that might help us to understand the resistance to drugs that 'starve’ tumours, and also how cancer cells manage to survive in the centre of the tumour mass, whe...

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Scientists at CIMA discover a gene that is necessary for cellular replication and the structure of the chromosomes

by CIMA - Centro de Investigación Médica Aplicada

Scientists at the Center for Applied Medical Research (CIMA) at the University of Navarra have discovered CONCR, a long non-coding RNA that regulates cell replication and the formation of the structur...

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Researchers discover the hidden potential of disordered proteins

by IRB Barcelona - Instituto de Investigación Biomédica

Prostate cancer, Alzheimer’s, Parkinson’s...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional s...

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Señalan una posible diana terapéutica contra la malaria y el 'mal de las vacas locas'

by Universidad de Sevilla

Investigadores de la Universidad de Sevilla, en colaboración con la Universidad de Ginebra en Suiza, han descubierto que ciertas proteínas implicadas en estas enfermedades ‘escapan’ del sistema ...

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Chaperones: nanomachines that transport and modify other proteins by stretching and colliding

by Centro Nacional de Biotecnología (CNB)

A study conducted jointly by scientists from the United States and Spain shows how Hsp70 chaperones work. As if they were nanomachines, the Hsp70 generate force on other proteins through collisions an...

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Asocian la activación de una ruta genética al índice de supervivencia en uno de los tipos de cáncer de mama

by INCLIVA

La activación de la vía NF-kB no canónica se asocia inversamente con la expresión del receptor de estrógeno en el cáncer de mama ER + y predice una baja supervivencia en este grupo de pacientes

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Un estudio del CIPF demuestra que una proteína podría potenciar la regeneración neuronal tras una lesión medular

by Centro de Investigación Príncipe Felipe

El estudio, llevado a cabo por la doctora Victoria Moreno, revela por primera vez que el canal iónico Conexina 50 está presente en grandes cantidades en las células madre de la médula espinal y qu...

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A new study sheds further light on vulnerabilities in aggressive breast cancer

by CIC bioGUNE

Triple negative breast cancer is characterised by a lack of markers indicating the most effective treatment strategies. A study led by the group of Dr. Arkaitz Carracedo in CIC bioGUNE identifies a pr...

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Sights set on the next generation of shuttle peptides to target the brain

by IRB Barcelona - Instituto de Investigación Biomédica

IRB Barcelona researchers publish a review article on the emerging field of drug transporters that have the capacity to reach the brain more efficiently. IRB Barcelona is one of the few centres worldw...

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