Se abre una nueva vía para combatir el cáncer a través del gen MYC

by ICO - Institut Català d'Oncologia

Un equipo de investigadores internacionales ha identificado los procesos específicos a través de los cuales el oncógeno MYC promueve la enfermedad y, de esta forma, demostrar que este gen puede ata...

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Secret Vulnerabilities of Cancer’s ‘Death Star’ Revealed

by Centre for Genomic Regulation

It has been identified the allosteric control sites found in the protein KRAS that are highly sought after targets for drug development, representing secret vulnerabilities which can be exploited to c...

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A new inactive form of p38a protein discovered

by IRB Barcelona - Instituto de Investigación Biomédica

38a protein, which is associated with cancer and other diseases, adopts a previously unknown structure regulated by cellular redox conditions

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3P Biopharmaceuticals: forjando un legado de innovación y excelencia en biotecnología

by 3P Biopharmaceuticals

La empresa recibe el premio a la Mejor Trayectoria Viveros CEIN en el Congreso Internacional de Emprendimiento de Alto Impacto

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The spin-off Peptomyc and VHIO awarded €4 million from the Spanish Ministry of Science and Innovation to advance the clinical development of the first MYC oncogene inhibitor

by VHIO

This funding covers advancement of the clinical development of OMO-103, Peptomyc’s first-in-class direct MYC inhibitor, as well as activities to explore its utility in combination with targeted agen...

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A new biochemical principle involving the interplay between oxidative stress and phosphorylation uncovered in aging

by IRB Lleida. Institut de Recerca Biomèdica

This study establishes, for the first time, a connection at the molecular level between oxidative stress and aberrant phosphorylation of proteins in the proteome, two fundamental mechanisms that inter...

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IrsiCaixa coordinates €5 Million EU-funded research project to tackle globally prevalent West Nile Virus

by IrsiCaixa

El personal científico involucrado trabajará en la ideación de estrategias capaces de prevenir y tratar la infección y enfermedad desencadenada por el Virus del Nilo Occidental, para el cual no ex...

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Nanopartículas proteicas con un nuevo ligando reconocen y destruyen selectivamente fibroblastos asociados a tumor

by Professional Newco

Han logrado un avance significativo al identificar el ligando natural PDGFD como una herramienta eficaz para direccionar nanopartículas proteicas a fibroblastos asociados a tumor que sobrexpresan el ...

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Accumulation of the protein versican is the cause of aortic aneurysm in Marfan syndrome

by Centro Nacional de Investigaciones Cardiovasculares - CNIC

A team led by scientists at the CNIC and CSIC has found that accumulation of versican in the aortas of Marfan syndrome patients triggers the activation of the nitric oxide pathway through the activati...

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Una mutación protectora frente a la enfermedad de Parkinson abre nuevas vías terapéuticas

by Revista Genética Médica

Las personas portadoras de una variante de la proteína mitocondrial SHLP2 tienen la mitad de probabilidad de desarrollar enfermedad de Parkinson, respecto a las personas no portadoras.

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BioExcel-CV19: A Breakthrough in Understanding COVID-19 Proteins

by IRB Barcelona - Instituto de Investigación Biomédica

Researchers at IRB Barcelona's Molecular Modelling and Bioinformatics lab have released a revolutionary database for molecular dynamics simulations.

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Smart skin bacteria are able to secrete and produce molecules to treat acne

by UPF - Universitat Pompeu Fabra

An experimental study led by the Translational Synthetic Biology Laboratory of Pompeu Fabra University has shown that a type of skin bacterium can efficiently be engineered to produce a protein to reg...

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